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纳米纤维垫的进展及常见的有用药物递送应用

Advancement of Nanofibrous Mats and Common Useful Drug Delivery Applications.

作者信息

Abu Owida Hamza, Al-Nabulsi Jamal I, Alnaimat Feras, Al Sharah Ashraf, Al-Ayyad Muhammad, Turab Nidal M, Abdullah Mustafa

机构信息

Medical Engineering Department, Faculty of Engineering, Al-Ahliyya Amman University, Amman 19328, Jordan.

Computer Engineering, Faculty of Engineering, Al-Ahliyya Amman University, Amman 19328, Jordan.

出版信息

Adv Pharmacol Pharm Sci. 2022 Apr 19;2022:9073837. doi: 10.1155/2022/9073837. eCollection 2022.

DOI:10.1155/2022/9073837
PMID:35492808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9042622/
Abstract

Electrospinning enables simple and cost-effective production of polymer nanofibers from different polymer materials. Drug delivery systems are capable of achieving maximum drug treatment benefits by significantly reducing adverse complications. Electrospun nanofibers have recently attracted considerable attention owing to their distinctive properties, including flexibility and biocompatibility. The implementation of functional constituents within nanostructure fibers blends is an effective technique for the administration of a variety of drugs in animal research, broadening the nanofiber capability and reliability. The nanofibrous mesh and its various application purposes are discussed in terms of a summary of recent research, emphasizing the ease of streaming and a large number of combinations of this approach, which could lead to a breakthrough in targeted therapy.

摘要

静电纺丝能够以简单且经济高效的方式由不同聚合物材料制备聚合物纳米纤维。药物递送系统能够通过显著减少不良并发症来实现最大的药物治疗效益。由于具有诸如柔韧性和生物相容性等独特性能,电纺纳米纤维近来备受关注。在纳米结构纤维共混物中引入功能成分是在动物研究中施用多种药物的有效技术,可拓展纳米纤维的能力和可靠性。根据近期研究综述讨论了纳米纤维网及其各种应用目的,强调了这种方法易于操作且有大量组合方式,这可能会带来靶向治疗方面的突破。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e638/9042622/bb91e0803949/APS2022-9073837.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e638/9042622/8638a9d50fee/APS2022-9073837.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e638/9042622/4527b75f7a3b/APS2022-9073837.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e638/9042622/bb91e0803949/APS2022-9073837.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e638/9042622/8638a9d50fee/APS2022-9073837.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e638/9042622/4527b75f7a3b/APS2022-9073837.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e638/9042622/bb91e0803949/APS2022-9073837.003.jpg

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