Liu Zuoyue, Jung Kyung Oh, Takahata Ryo, Sakamoto Masanori, Teranishi Toshiharu, Fujitsuka Mamoru, Pratx Guillem, Osakada Yasuko
The Institute of Scientific and Industrial Research (SANKEN), Osaka University Mihogaoka 8-1 Osaka 567-0047 Ibaraki Japan
Department of Radiation Oncology and Medical Physics, Stanford University 300 Pasteur Dr Stanford CA 94305 USA.
RSC Adv. 2020 Apr 6;10(23):13824-13829. doi: 10.1039/d0ra01935f. eCollection 2020 Apr 1.
Hard X-ray excited optical luminescence is a unique property of materials, which makes them promising for biological imaging applications. However, the preparation of biocompatible contrast agents for hard X-ray excited optical luminescence remains a considerable challenge that has, to date, not been overcome. In this study, we investigated the luminescence properties of protein-directed Au clusters upon hard X-ray irradiation, both in solution and when embedded in films.
硬X射线激发的光学发光是材料的一种独特性质,这使其在生物成像应用方面具有广阔前景。然而,制备用于硬X射线激发光学发光的生物相容性造影剂仍然是一个巨大的挑战,迄今为止尚未得到解决。在本研究中,我们研究了蛋白质导向的金簇在硬X射线辐照下在溶液中和嵌入薄膜时的发光特性。