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蛋白质导向金簇的硬X射线激发光学发光

Hard X-ray excited optical luminescence from protein-directed Au clusters.

作者信息

Liu Zuoyue, Jung Kyung Oh, Takahata Ryo, Sakamoto Masanori, Teranishi Toshiharu, Fujitsuka Mamoru, Pratx Guillem, Osakada Yasuko

机构信息

The Institute of Scientific and Industrial Research (SANKEN), Osaka University Mihogaoka 8-1 Osaka 567-0047 Ibaraki Japan

Department of Radiation Oncology and Medical Physics, Stanford University 300 Pasteur Dr Stanford CA 94305 USA.

出版信息

RSC Adv. 2020 Apr 6;10(23):13824-13829. doi: 10.1039/d0ra01935f. eCollection 2020 Apr 1.

Abstract

Hard X-ray excited optical luminescence is a unique property of materials, which makes them promising for biological imaging applications. However, the preparation of biocompatible contrast agents for hard X-ray excited optical luminescence remains a considerable challenge that has, to date, not been overcome. In this study, we investigated the luminescence properties of protein-directed Au clusters upon hard X-ray irradiation, both in solution and when embedded in films.

摘要

硬X射线激发的光学发光是材料的一种独特性质,这使其在生物成像应用方面具有广阔前景。然而,制备用于硬X射线激发光学发光的生物相容性造影剂仍然是一个巨大的挑战,迄今为止尚未得到解决。在本研究中,我们研究了蛋白质导向的金簇在硬X射线辐照下在溶液中和嵌入薄膜时的发光特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4824/9051530/82ca889b87fd/d0ra01935f-f1.jpg

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