Department of Burns and Plastic and Wound Repair Surgery, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
School of Medicine, Xiamen University, Xiamen, China.
Front Cell Infect Microbiol. 2022 Apr 12;12:861053. doi: 10.3389/fcimb.2022.861053. eCollection 2022.
Dermatitis is an important global health problem that not only affects social interaction and physical and mental health but also causes economic burden. Health problems or distress caused by dermatitis may be easily overlooked, and relevant epidemiological data are limited. Therefore, a better understanding of the burden of dermatitis is necessary for developing global intervention strategies.
All data on dermatitis, including atopic dermatitis (AD), contact dermatitis (CD) and seborrhoeic dermatitis (SD), were obtained from the Global Burden of Disease 2019 (GBD2019) database. The extracted age-standardized incidence rates (ASIR) and disability-adjusted life-years (DALYs) rates (ASDR) data were analysed by stratification, including by sex, country or region, and sociodemographic index (SDI) indicators. Finally, we analysed the correlation between the global burden of dermatitis and socioeconomic development status.
According to the GBD 2019 estimate, the ASIR and ASDR for the three major types of dermatitis in 2019 were 5244.3988 (95% CI 4551.7244-5979.3176) per 100,000 person-years and 131.6711 (95% CI 77.5876-206.8796) per 100,000 person-years. The ASIR and ASDR of atopic dermatitis, contact dermatitis and seborrhoeic dermatitis are: Incidence (95%CI,per 100,000 person-years), 327.91 (312.76-343.67), 3066.04 (2405.38-3755.38), 1850.44 (1706.25- 1993.74); DALYs (95%CI, per 100,000 person-years), 99.69 (53.09-167.43), 28.06 (17.62-41.78), 3.93 (2.24-6.25). In addition, among the three dermatitis types, the greatest burden was associated with AD. According to the ASDR from 1990 to 2019, the burden of dermatitis has exhibited a slow downward trend in recent years. In 2019, the ASIR showed that the USA had the greatest burden, while the ASDR showed that Asian countries (such as Japan, Mongolia, Kazakhstan, and Uzbekistan) and some European countries (France, Estonia) had the greatest burden. According to SDI stratification and the three major dermatitis types, high ASIR and ASDR corresponded to high SDI areas (especially for AD).
The burden of dermatitis is related to socioeconomic development status, especially for AD, which is positively correlated with the SDI. The results based on GBD2019 data are valuable for formulating policy, preventing and treating dermatitis and reducing the global burden of dermatitis.
皮炎是一个重要的全球性健康问题，不仅影响社交互动和身心健康，还会造成经济负担。皮炎引起的健康问题或痛苦可能很容易被忽视，相关的流行病学数据也有限。因此，了解皮炎的负担对于制定全球干预策略非常必要。
所有关于皮炎的数据，包括特应性皮炎（AD）、接触性皮炎（CD）和脂溢性皮炎（SD），均从 2019 年全球疾病负担（GBD2019）数据库中获得。通过分层分析提取的年龄标准化发病率（ASIR）和伤残调整生命年（DALY）率（ASDR）数据，包括性别、国家或地区和社会人口学指数（SDI）指标。最后，我们分析了皮炎的全球负担与社会经济发展状况之间的相关性。
根据 GBD2019 的估计，2019 年三种主要皮炎类型的 ASIR 和 ASDR 分别为每 100000 人年 5244.3988（95%CI 4551.7244-5979.3176）和每 100000 人年 131.6711（95%CI 77.5876-206.8796）。特应性皮炎、接触性皮炎和脂溢性皮炎的 ASIR 和 ASDR 分别为：发病率（95%CI，每 100000 人年），327.91（312.76-343.67）、3066.04（2405.38-3755.38）、1850.44（1706.25-1993.74）；伤残调整生命年（95%CI，每 100000 人年），99.69（53.09-167.43）、28.06（17.62-41.78）、3.93（2.24-6.25）。此外，在三种皮炎类型中，AD 造成的负担最大。根据 1990 年至 2019 年的 ASDR，近年来皮炎的负担呈缓慢下降趋势。2019 年，ASIR 显示美国的负担最大，而 ASDR 显示亚洲国家（如日本、蒙古、哈萨克斯坦和乌兹别克斯坦）和一些欧洲国家（法国、爱沙尼亚）的负担最大。根据 SDI 分层和三种主要的皮炎类型，高 ASIR 和 ASDR 对应高 SDI 地区（尤其是 AD）。
皮炎的负担与社会经济发展状况有关，特别是 AD，与 SDI 呈正相关。基于 GBD2019 数据的结果对于制定政策、预防和治疗皮炎以及减轻全球皮炎负担非常有价值。
