Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, No.32, Renmin South Road, Shiyan, 442000, China.
Department of Emergency, Taihe Hospital, Hubei University of Medicine, No.32, South Renmin Road, Shiyan, 442000, China.
BMC Public Health. 2023 Apr 19;23(1):714. doi: 10.1186/s12889-023-15539-5.
Myocarditis, a health-threatening heart disease, is attracting increasing attention. This systematic study was conducted to study the prevalence of disease through the trends of incidence, mortality, disability-adjusted life years (DALYs) over the last 30 years, which would be helpful for the policymakers to better the choices for reasonable decisions.
The global, regional, and national burdens of myocarditis from 1990-2019 were analyzed by using the 2019 Global Burden of Disease (GBD) database. This study on myocarditis produced new findings according to age, sex, and Social-Demographic Index (SDI) by investigating DALYs, age-standardized incidence rate (ASIR), age-standardized death rate (ASDR), and corresponding estimated annual percentage change (EAPC).
The number of myocarditis incidence increased by 62.19%, from 780,410 cases in 1990 to 1,265,770 cases in 2019. The ASIR decreased by 4.42% (95%CI, from -0.26% to -0.21%) over the past 30 years. The number of deaths from myocarditis increased by 65.40% from 19,618 in 1990 to 324,490 in 2019, but the ASDR was relatively stable over the investigated period. ASDR increased in low-middle SDI regions (EAPC=0.48; 95%CI, 0.24 to 0.72) and decreased in low SDI regions (EAPC=-0.97; 95%CI, from -1.05 to -0.89). The age-standardized DALY rate decreased by 1.19% (95%CI, from -1.33% to -1.04%) per year.
Globally, the ASIR and DALY for myocarditis decreased and the ASDR was stable over the past 30 years. The risk of incidences and death cases increased with age. Measures should be taken to control the risk of myocarditis in high-burden regions. Medical supplies should be improved in the high-middle SDI regions and middle SDI regions to reduce the deaths from myocarditis in these regions.
心肌炎是一种威胁生命的心脏疾病，正受到越来越多的关注。本系统研究旨在通过过去 30 年的发病率、死亡率和伤残调整生命年（DALY）趋势来研究疾病的流行情况，这将有助于决策者做出更好的合理决策。
利用 2019 年全球疾病负担（GBD）数据库，分析 1990 年至 2019 年全球、区域和国家心肌炎负担。本研究根据年龄、性别和社会人口指数（SDI），通过调查 DALY、年龄标准化发病率（ASIR）、年龄标准化死亡率（ASDR）和相应的估计年百分比变化（EAPC），得出新的发现。
心肌炎发病率增加了 62.19%，从 1990 年的 780410 例增加到 2019 年的 1265770 例。在过去 30 年中，ASIR 下降了 4.42%（95%CI：-0.26%至-0.21%）。心肌炎死亡人数从 1990 年的 19618 例增加到 2019 年的 324490 例，增加了 65.40%，但在此期间 ASDR 相对稳定。低-中 SDI 地区的 ASDR 增加（EAPC=0.48；95%CI：0.24 至 0.72），低 SDI 地区的 ASDR 下降（EAPC=-0.97；95%CI：从-1.05 至-0.89）。年龄标准化 DALY 率每年下降 1.19%（95%CI：从-1.33%至-1.04%）。
在过去 30 年中，全球心肌炎的 ASIR 和 DALY 下降，ASDR 保持稳定。发病率和死亡人数随年龄增长而增加。应采取措施控制高负担地区心肌炎的风险。应改善中-高 SDI 地区和中 SDI 地区的医疗供应，以降低这些地区的心肌炎死亡率。
