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“CinNapht”染料:一种新型噌啉/萘酰亚胺稠合杂化荧光团。合成、光物理研究及其在生物成像中的应用。

"CinNapht" dyes: a new cinnoline/naphthalimide fused hybrid fluorophore. Synthesis, photo-physical study and use for bio-imaging.

作者信息

Hoang Minh-Duc, Bodin Jean-Baptiste, Savina Farah, Steinmetz Vincent, Bignon Jérôme, Durand Philippe, Clavier Gilles, Méallet-Renault Rachel, Chevalier Arnaud

机构信息

Université Paris-Saclay, CNRS, Institut de Chimie des Substances Naturelles UPR 2301 91198 Gif-sur-Yvette France

Université Paris-Saclay, CNRS, Institut des Sciences Moléculaires d'Orsay Orsay 91405 France.

出版信息

RSC Adv. 2021 Sep 8;11(48):30088-30092. doi: 10.1039/d1ra05110e. eCollection 2021 Sep 6.

Abstract

Six-membered-diaza ring of cinnoline has been fused on naphthalimide dye to give a donor-acceptor system called CinNapht. This red shifted fluorophore, that can be synthesised in gram scale, exhibits a large Stoke shift and a fluorescence quantum yield up to 0.33. It is also characterized by a strong solvatochromic effect from green to red emission as well and can be used for bio-imaging.

摘要

噌啉的六元二氮杂环与萘酰亚胺染料稠合,形成了一种名为CinNapht的供体-受体体系。这种红移荧光团可大规模合成,具有较大的斯托克斯位移和高达0.33的荧光量子产率。它还具有从绿色到红色发射的强烈溶剂化显色效应,可用于生物成像。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4b2/9041350/a3ec44fe6c3c/d1ra05110e-f1.jpg

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