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妊娠合并登革热综合管理指南的必要性:来自印度一家三级护理妇产医院的回顾性研究

Need for guidelines for the combined management of pregnancy and dengue: a retrospective study from an Indian tertiary care maternity hospital.

作者信息

Kallur Sailaja Devi, Surapaneni Tarakeswari, Boorugu Hari Kishan, Aziz Nuzhat, Gala Anisha Ramniklal, Donnuri Swathi

机构信息

Consultant obstetrician, Department of Obstetrics, Fernandez Hospital, Telangana, Hyderabad, India.

出版信息

Trop Doct. 2019 Jan;49(1):7-9. doi: 10.1177/0049475518800638. Epub 2018 Sep 30.

DOI:10.1177/0049475518800638
PMID:30270767
Abstract

The incidence of dengue has risen in India in recent years. Evidence suggests that dengue in pregnancy may be associated with adverse maternal and fetal outcomes. The aim of our study was to analyse outcomes in pregnant women with confirmed dengue infection who had the benefit of close monitoring and intensive management at a tertiary maternity facility. We reviewed hospital data of 44 (0.11%) such women at Fernandez Hospital, a tertiary maternity unit, during the five-year period from 2011 to 2016. Maternal and fetal variables were collected from case sheets. Dengue haemorrhagic fever was seen in 15.9% and dengue shock syndrome in one fatal case (2.2%). Thrombocytopenia was seen in 31 cases (70.4%) and 14 (31.81%) received platelets transfusions. Fetal outcomes in our series were favourable, except for one stillbirth, with 45.4% preterm deliveries and 15.9% small for gestational age babies. Dengue in pregnancy is definitely associated with maternal and fetal morbidity and mortality. A high index of suspicion of dengue is required in pregnant women with pyrexia and thrombocytopenia.

摘要

近年来,印度登革热的发病率有所上升。有证据表明,孕期登革热可能与孕产妇和胎儿的不良结局有关。我们研究的目的是分析在一家三级产科机构接受密切监测和强化管理的确诊登革热感染孕妇的结局。我们回顾了2011年至2016年五年期间,费尔南德斯医院(一家三级产科单位)44名(0.11%)此类孕妇的医院数据。从病历中收集孕产妇和胎儿变量。15.9%的患者出现登革出血热,1例(2.2%)出现登革休克综合征并死亡。31例(70.4%)出现血小板减少,14例(31.81%)接受了血小板输注。除1例死产外,我们系列中的胎儿结局良好,45.4%为早产,15.9%为小于胎龄儿。孕期登革热肯定与孕产妇和胎儿的发病率及死亡率有关。对于发热和血小板减少的孕妇,需要高度怀疑登革热。

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