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Researchers' Ethical Concerns About Using Adaptive Deep Brain Stimulation for Enhancement.

作者信息

Kostick-Quenet Kristin, Kalwani Lavina, Koenig Barbara, Torgerson Laura, Sanchez Clarissa, Munoz Katrina, Hsu Rebecca L, Sierra-Mercado Demetrio, Robinson Jill Oliver, Outram Simon, Pereira Stacey, McGuire Amy, Zuk Peter, Lazaro-Munoz Gabriel

机构信息

Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX, United States.

Center for Medical Ethics and Health Policy, Baylor College of Medicine, Rice University, Houston, TX, United States.

出版信息

Front Hum Neurosci. 2022 Apr 14;16:813922. doi: 10.3389/fnhum.2022.813922. eCollection 2022.


DOI:10.3389/fnhum.2022.813922
PMID:35496073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9050172/
Abstract

The capacity of next-generation closed-loop or adaptive deep brain stimulation devices (aDBS) to read (measure neural activity) and write (stimulate brain regions or circuits) shows great potential to effectively manage movement, seizure, and psychiatric disorders, and also raises the possibility of using aDBS to electively (non-therapeutically) modulate mood, cognition, and prosociality. What separates aDBS from most neurotechnologies (e.g. transcranial stimulation) currently used for enhancement is that aDBS remains an invasive, surgically-implanted technology with a risk-benefit ratio significantly different when applied to diseased versus non-diseased individuals. Despite a large discourse about the ethics of enhancement, no empirical studies yet examine perspectives on enhancement from within the aDBS research community. We interviewed 23 aDBS researchers about their attitudes toward expanding aDBS use for enhancement. A thematic content analysis revealed that researchers share ethical concerns related to (1) safety and security; (2) enhancement as unnecessary, unnatural or aberrant; and (3) fairness, equality, and distributive justice. Most (70%) researchers felt that enhancement applications for DBS will eventually be technically feasible and that attempts to develop such applications for DBS are already happening (particularly for military purposes). However, researchers unanimously (100%) felt that DBS ideally should not be considered for enhancement until researchers better understand brain target localization and functioning. While many researchers acknowledged controversies highlighted by scholars and ethicists, such as potential impacts on personhood, authenticity, autonomy and privacy, their ethical concerns reflect considerations of both gravity and perceived near-term likelihood.

摘要

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[1]
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[2]
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[3]
Electrical and Magnetic Neuromodulation Technologies and Brain-Computer Interfaces: Ethical Considerations for Enhancement of Brain Function in Healthy People - A Systematic Scoping Review.

Stereotact Funct Neurosurg. 2024

[4]
Ethical considerations for integrating multimodal computer perception and neurotechnology.

Front Hum Neurosci. 2024-2-16

[5]
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[6]
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[7]
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[8]
A Call for Behavioral Science in Embedded Bioethics.

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本文引用的文献

[1]
DBS and Autonomy: Clarifying the Role of Theoretical Neuroethics.

Neuroethics. 2021-10

[2]
Researcher Perspectives on Data Sharing in Deep Brain Stimulation.

Front Hum Neurosci. 2020-12-17

[3]
Researcher Perspectives on Ethical Considerations in Adaptive Deep Brain Stimulation Trials.

Front Hum Neurosci. 2020-11-12

[4]
The Hybridization of the Human with Brain Implants: The Neuralink Project.

Camb Q Healthc Ethics. 2020-10

[5]
Understanding brain organisation in the face of functional heterogeneity and functional multiplicity.

Neuroimage. 2020-10-15

[6]
An Integrated Brain-Machine Interface Platform With Thousands of Channels.

J Med Internet Res. 2019-10-31

[7]
Neuralink: The Ethical 'Rithmatic of Reading and Writing to the Brain.

AJOB Neurosci. 2019

[8]
Dimensions of Ethical Direct-to-Consumer Neurotechnologies.

AJOB Neurosci. 2019

[9]
Device Removal Following Brain Implant Research.

Neuron. 2019-9-4

[10]
The ethics of neurotechnology.

Nat Biotechnol. 2019-9

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