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锰掺杂普鲁士蓝纳米颗粒的阿霉素释放与双光子照射在癌症治疗中的协同效应。

Synergic effect of doxorubicin release and two-photon irradiation of Mn-doped Prussian blue nanoparticles on cancer therapy.

作者信息

Ali Lamiaa M A, Mathlouthi Emna, Cahu Maëlle, Sene Saad, Daurat Morgane, Long Jérôme, Guari Yannick, Salles Fabrice, Chopineau Joël, Devoisselle Jean-Marie, Larionova Joulia, Gary-Bobo Magali

机构信息

Institut des Biomolécules Max Mousseron, UMR5247, Université de Montpellier, CNRS, ENSCM, Faculté de Pharmacie 15 Avenue Charles Flahault 34093 Montpellier Cedex 05 France

Department of Biochemistry, Medical Research Institute, University of Alexandria Alexandria Egypt.

出版信息

RSC Adv. 2020 Jan 15;10(5):2646-2649. doi: 10.1039/c9ra09133e. eCollection 2020 Jan 14.

DOI:10.1039/c9ra09133e
PMID:35496092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9048416/
Abstract

We demonstrate here that Mn-doped Prussian blue nanoparticles of 55 nm loaded with doxorubicin may be used as efficient therapeutic agents for combined photothermal and chemo-therapy of cancer cells with a synergic effect under two photon irradiation.

摘要

我们在此证明，负载阿霉素的55纳米锰掺杂普鲁士蓝纳米颗粒可作为高效治疗剂，用于在双光子照射下对癌细胞进行光热和化疗联合治疗，并具有协同效应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad58/9048416/7fadc821580c/c9ra09133e-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad58/9048416/c0dd711db89e/c9ra09133e-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad58/9048416/724fe5f650fe/c9ra09133e-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad58/9048416/7fadc821580c/c9ra09133e-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad58/9048416/c0dd711db89e/c9ra09133e-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad58/9048416/724fe5f650fe/c9ra09133e-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad58/9048416/7fadc821580c/c9ra09133e-f3.jpg

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Biocompatible semiconducting polymer nanoparticles as robust photoacoustic and photothermal agents revealing the effects of chemical structure on high photothermal conversion efficiency.
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Toward Understanding Drug Incorporation and Delivery from Biocompatible Metal-Organic Frameworks in View of Cutaneous Administration.从皮肤给药角度理解生物相容性金属有机框架中的药物掺入与递送
ACS Omega. 2018 Mar 31;3(3):2994-3003. doi: 10.1021/acsomega.8b00185. Epub 2018 Mar 12.
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