Zahra Urage, Saeed Aamer, Abdul Fattah Tanzeela, Flörke Ulrich, Erben Mauricio F
Department of Chemistry, Quaid-i-Azam University-45320 Islamabad Pakistan
Department Chemie, Fakultät für Naturwissenschaften, Universität Paderborn Warburgerstrasse 100 D-33098 Paderborn Germany.
RSC Adv. 2022 Apr 26;12(20):12710-12745. doi: 10.1039/d2ra01781d. eCollection 2022 Apr 22.
The interest in acyl thioureas has continually been escalating owing to their extensive applications in diverse fields, such as synthetic precursors of new heterocycles, pharmacological and materials science, and technology. These scaffolds exhibit a wide variety of biological activities such as antitumor, enzyme inhibitory, anti-bacterial, anti-fungal, and anti-malarial activities and find utilization as chemosensors, adhesives, flame retardants, thermal stabilizers, antioxidants, polymers and organocatalysts. In addition, the synthesis, and applications of coordination complexes of these ligands have also been overviewed. The current review is a continuation of our previous efforts in this area, focusing on the recent advancements during the period 2017 to present.
由于酰基硫脲在新杂环的合成前体、药理学、材料科学和技术等不同领域有着广泛应用，人们对其的兴趣一直在不断上升。这些骨架展现出各种各样的生物活性，如抗肿瘤、酶抑制、抗菌、抗真菌和抗疟活性，并且可用作化学传感器、粘合剂、阻燃剂、热稳定剂、抗氧化剂、聚合物和有机催化剂。此外，这些配体的配位络合物的合成及应用也已得到综述。本综述是我们此前在该领域工作的延续，重点关注2017年至今的最新进展。
