Zhang Jiahui, Zhao Ying, Tian Zilu, Zhu Jiufu, Shi Zuosen, Cui Zhanchen, Zhu Song
Department of Prosthetic Dentistry, School and Hospital of Stomatology, Jilin University Changchun 130021 P. R. China
State Key Lab of Supramolecular Structure and Materials, College of Chemistry, Jilin University Changchun 130021 P. R. China.
RSC Adv. 2020 Mar 24;10(20):12035-12046. doi: 10.1039/c9ra10992g. eCollection 2020 Mar 19.
In this study, we evaluated bioinspired adhesive primers for durable adhesion between dentin and composite resins. -3,4-Dihydroxyphenethyl methacrylamide (DMA) primer monomer (small bifunctional group molecules containing catechol and acrylic groups at opposite ends) was prepared to mimic the interaction between the catechol group and the mineral interface of marine mussels. The shear bonding strength, microleakage, degree of conversion, contact angle, and compatibility were tested. The shear bond strength was significantly improved, and microleakage was diminished after the application of the DMA primer. However, the degree of conversion was decreased. The wettability of the dentin was enhanced, and the DMA primer showed no negative influence on cell proliferation. The results of this study showed the possibility of using DMA primers in clinical practice. This may provide a new strategy for improving adhesion durability.
在本研究中，我们评估了用于牙本质与复合树脂之间持久黏附的仿生黏附底漆。制备了3,4-二羟基苯乙基甲基丙烯酰胺（DMA）底漆单体（两端分别含有儿茶酚和丙烯酸基团的小双官能团分子），以模拟儿茶酚基团与海洋贻贝矿物界面之间的相互作用。测试了剪切粘结强度、微渗漏、转化率、接触角和相容性。应用DMA底漆后，剪切粘结强度显著提高，微渗漏减少。然而，转化率降低。牙本质的润湿性增强，且DMA底漆对细胞增殖无负面影响。本研究结果表明了在临床实践中使用DMA底漆的可能性。这可能为提高黏附耐久性提供一种新策略。
