Heravi Majid M, Amiri Zahra, Kafshdarzadeh Kosar, Zadsirjan Vahideh
Department of Chemistry, School of Physics and Chemistry, Alzahra University Vanak Tehran Iran
RSC Adv. 2021 Oct 15;11(53):33540-33612. doi: 10.1039/d1ra05972f. eCollection 2021 Oct 8.
Indoles are a significant heterocyclic system in natural products and drugs. They are important types of molecules and natural products and play a main role in cell biology. The application of indole derivatives as biologically active compounds for the treatment of cancer cells, microbes, and different types of disorders in the human body has attracted increasing attention in recent years. Indoles, both natural and synthetic, show various biologically vital properties. Owing to the importance of this significant ring system, the investigation of novel methods of synthesis have attracted the attention of the chemical community. In this review, we aim to highlight the construction of indoles as a moiety in selected alkaloids.
吲哚是天然产物和药物中重要的杂环体系。它们是重要的分子类型和天然产物，在细胞生物学中发挥着主要作用。近年来，吲哚衍生物作为具有生物活性的化合物用于治疗癌细胞、微生物以及人体的各种疾病，已引起越来越多的关注。天然和合成的吲哚都具有各种重要的生物学特性。由于这个重要环系的重要性，新型合成方法的研究已引起化学界的关注。在本综述中，我们旨在突出吲哚作为选定生物碱中一个部分的构建。
