Department of Chemistry, University of Isfahan, Isfahan 81746-73441, Iran.
Department of Chemistry, Faculty of Physics and Chemistry, Alzahra University, Vanak, Tehran 19938-91176, Iran.
Molecules. 2024 Jan 18;29(2):484. doi: 10.3390/molecules29020484.
Indole is an important element of many natural and synthetic molecules with significant biological activity. Nonetheless, the co-presence of transitional metals in organic scaffold may represent an important factor in the development of effective medicinal agents. This review covers some of the latest and most relevant achievements in the biological and pharmacological activity of important indole-containing metal complexes in the area of drug discovery.
吲哚是许多具有重要生物活性的天然和合成分子的重要组成部分。然而，过渡金属在有机支架中的共存可能是开发有效药物的一个重要因素。本文综述了在药物发现领域中一些最新和最重要的含吲哚金属配合物的生物和药理学活性的研究进展。
