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FAST泵,一种低成本、易于制造的、通过立体光刻3D打印的蠕动泵,适用于任何实验室的多通道系统。

The FAST Pump, a low-cost, easy to fabricate, SLA-3D-printed peristaltic pump for multi-channel systems in any lab.

作者信息

Jönsson Alexander, Toppi Arianna, Dufva Martin

机构信息

DTU Health Tech, Technical University of Denmark, Kgs Lyngby, Denmark.

出版信息

HardwareX. 2020 Jun 7;8:e00115. doi: 10.1016/j.ohx.2020.e00115. eCollection 2020 Oct.

Abstract

With the increasing interest in high throughput screening and parallel assays, laboratories around the world inevitably find themselves in need of driving a multitude of fluid lines to facilitate their large scale studies. The comparatively low cost and no-fluid-contact design of peristaltic pumps make them the go-to systems for such ventures, but using commercially available pumping systems this still becomes a costly endeavor at typically $250-$1000 per pump line. Here we have developed an alternative, a peristaltic pump that can be fabricated in most research laboratories using 3D-printing and readily available off-the-shelf parts. The pump features 8 parallel channels with linear ranges spanning from 0.7 µL/min to 6 mL/min. The pump can be fabricated and assembled by anyone with access to a 3D-printer at a cost of less than $45 per channel and is driven by a stepper motor that connects directly to any computer. This device has the potential to be disruptive in areas such as drug screening and assay development, as well as lab-on-a-chip applications and cell cultivation, where it significantly reduces hardware expenses and allows for construction of more comprehensive fluidic systems at a fraction of current costs.

摘要

随着对高通量筛选和平行分析的兴趣日益浓厚,世界各地的实验室不可避免地发现自己需要驱动大量流体管路以促进其大规模研究。蠕动泵相对较低的成本和无流体接触设计使其成为此类项目的首选系统,但使用市售的泵送系统,每条泵管路的成本通常仍高达250至1000美元,这仍然是一项昂贵的工作。在此,我们开发了一种替代方案,一种蠕动泵,大多数研究实验室可以使用3D打印和现成的零部件制造。该泵具有8个平行通道,线性范围从0.7微升/分钟到6毫升/分钟。任何能够使用3D打印机的人都可以制造和组装该泵,每个通道的成本不到45美元,并且由直接连接到任何计算机的步进电机驱动。该设备在药物筛选、分析开发以及芯片实验室应用和细胞培养等领域可能具有颠覆性,因为它显著降低了硬件成本,并允许以当前成本的一小部分构建更全面的流体系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6a7/9041223/48ebce414b4a/ga1.jpg

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