生物规格：一种开源台式平行生物反应器系统。
BIO-SPEC: An open-source bench-top parallel bioreactor system.
作者信息
Parret Laurens, Simoens Kenneth, De Vrieze Jo, Smets Ilse
机构信息
KU Leuven - Department of Chemical Engineering, Chemical and biochemical Reactor Engineering and Safety (CREaS), KU Leuven, Celestijnenlaan 200F box 2424, B-3001 Leuven, Belgium.
Center for Microbial Ecology and Technology (CMET), Ghent University, Coupure Links 653, B- 9000 Ghent, Belgium.
出版信息
HardwareX. 2025 Jul 25;23:e00670. doi: 10.1016/j.ohx.2025.e00670. eCollection 2025 Sep.
The BIO-SPEC is an open-source, cost-effective, and modular bench-top bioreactor system designed for batch, sequencing batch, and chemostat cultivation. Featuring thermoelectric condensers to eliminate the need for a chiller, it ensures stable long-term operation. Controlled by a Raspberry Pi, the BIO-SPEC offers flexibility in headplate design, gas supply, and feeding strategies, making it a versatile alternative to high-cost commercial systems. This paper details the design, construction, and validation of the BIO-SPEC system, demonstrating its potential to advance microbiology and bioprocessing research through accessible and reliable hardware at a fraction of the cost of commercial systems.
BIO-SPEC是一种开源、经济高效且模块化的台式生物反应器系统，设计用于分批、序批和恒化培养。它配备了热电冷凝器，无需使用冷却器，确保了长期稳定运行。由树莓派控制，BIO-SPEC在顶板设计、气体供应和进料策略方面具有灵活性，是高成本商业系统的通用替代品。本文详细介绍了BIO-SPEC系统的设计、构建和验证，展示了其以商业系统成本的一小部分通过可访问且可靠的硬件推进微生物学和生物加工研究的潜力。
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