More Simon J, McAloon Catherine, Silva Boloña Pablo, O'Grady Luke, O'Sullivan Frank, McGrath Michelle, Buckley Willie, Downing Kevin, Kelly Patrick, Ryan Eoin G, McCoy Finola
Centre for Veterinary Epidemiology and Risk Analysis, UCD School of Veterinary Medicine, University College Dublin, Belfield, Ireland.
Herd Health and Animal Husbandry, UCD School of Veterinary Medicine, University College Dublin, Belfield, Ireland.
Front Vet Sci. 2022 Apr 11;9:748353. doi: 10.3389/fvets.2022.748353. eCollection 2022.
The Veterinary Medicines Regulation (EU 2019/6) came into force in all EU member states on 28 January 2022. This regulation places particular emphasis on prudent and responsible antimicrobial use in food animal production. Key changes include restrictions on the prophylactic use of antimicrobials in animals, and the possibility to reserve certain antimicrobials for humans only. The Regulation presents challenges to the Irish dairy industry, particularly with respect to current approaches to dry cow therapy. In response, the CellCheck technical working group (TWG, a technical group working in support of CellCheck, the national mastitis control programme) have developed pragmatic national and farm-level recommendations in support of improved mastitis control and intramammary antimicrobial stewardship in the Irish dairy industry. This paper outlines these recommendations, and provides an overview of the evidence considered to inform the TWG during its work (including the Regulation, policy perspectives, international best-practice, international scientific reviews and specific Irish challenges). In many key areas of concern, the TWG recognises the challenges in seeking to shape recommendations in the absence of robust and practical scientific evidence. For this reason, some of the recommended actions are pragmatic in nature, informed by national and international experiences. Periodic programme review will be needed, informed by ongoing monitoring of key performance indicators, to identify those actions that are most effective in an Irish context.
《兽药法规》（欧盟2019/6）于2022年1月28日在所有欧盟成员国生效。该法规特别强调在食用动物生产中谨慎和负责任地使用抗菌药物。主要变化包括限制在动物中预防性使用抗菌药物，以及将某些抗菌药物仅保留给人类使用的可能性。该法规给爱尔兰乳制品行业带来了挑战，特别是在当前干奶牛治疗方法方面。作为回应，CellCheck技术工作组（TWG，一个支持国家乳腺炎控制计划CellCheck的技术小组）制定了务实的国家和农场层面的建议，以支持爱尔兰乳制品行业改善乳腺炎控制和乳房内抗菌药物管理。本文概述了这些建议，并提供了在TWG工作期间为其提供信息的证据概述（包括该法规、政策观点、国际最佳实践、国际科学综述和爱尔兰的具体挑战）。在许多关键关注领域，TWG认识到在缺乏有力和实用科学证据的情况下制定建议所面临的挑战。因此，一些建议行动本质上是务实的，以国家和国际经验为依据。需要根据对关键绩效指标的持续监测进行定期的项目审查，以确定在爱尔兰背景下最有效的那些行动。
