各种提取技术对鼠尾草（L.）精油质量的影响，通过化学成分、热性质和生物活性来体现。
The effect of various extraction techniques on the quality of sage ( L.) essential oil, expressed by chemical composition, thermal properties and biological activity.
作者信息
Đurović Saša, Micić Darko, Pezo Lato, Radić Danka, Bazarnova Julia G, Smyatskaya Yulia A, Blagojević Stevan
机构信息
Institute of General and Physical Chemistry, Studentski trg 12, 11158 Belgrade, Serbia.
Peter the Great Saint-Petersburg Polytechnic University, Graduate School of Biotechnology and Food Industries, Polytechnicheskaya street, 29, 195251 Saint-Petersburg, Russia.
出版信息
Food Chem X. 2022 Jan 19;13:100213. doi: 10.1016/j.fochx.2022.100213. eCollection 2022 Mar 30.
In this study, influence of the extraction techniques on the quality of the sage essential oil was investigated. Obtained samples were analyzed for chemical composition by GC/MS, thermal properties by thermogravimetric analysis (TGA), and for biological activity: antioxidant (DPPH, CUPRAC, FRAP, ABTS, HRSA and TBARS), microbiological (, , , , and ), and cytotoxic (HeLa, LS-174, A549 and MRC-5) activities. Chemical composition showed that viridiflorol was principal compound in all samples followed by camphor, thujones, and verticiol. MWD 400 W was the most potent antioxidant agent, D 200 W and MWD 400 W antimicrobial agents, while hydrodistallates (D 200 W and D 400 W) were the most potent cytotoxic agents. An artificial neural network model was developed for the antioxidant activity anticipation of analyzed samples. These models showed good prediction properties (the value during training cycle for output variables was 0.998).
在本研究中，考察了提取技术对鼠尾草精油质量的影响。通过气相色谱/质谱联用仪（GC/MS）对所得样品的化学成分进行分析，通过热重分析（TGA）测定其热性能，并检测其生物活性：抗氧化活性（DPPH、CUPRAC、FRAP、ABTS、HRSA和TBARS）、微生物活性（，，，，和）以及细胞毒性（HeLa、LS-174、A549和MRC-5）。化学成分分析表明，所有样品中的主要化合物为绿花白千层醇，其次是樟脑、侧柏酮和垂叶松醇。MWD 400 W是最有效的抗氧化剂，D 200 W和MWD 400 W是抗菌剂，而水蒸馏物（D 200 W和D 400 W）是最有效的细胞毒性剂。建立了人工神经网络模型用于预测分析样品的抗氧化活性。这些模型显示出良好的预测性能（训练周期内输出变量的 值为0.998）。
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