Raal Ain, Orav Anne, Arak Elmar
Institute of Pharmacy, University of Tartu, Estonia.
Nat Prod Res. 2007 May;21(5):406-11. doi: 10.1080/14786410500528478.
Variations in the essential oil composition of Salvia officinalis L. growing in Estonia and in other European countries were determined. The oils were obtained in yields of 2.2-24.8 mL kg(-1). In three samples, the content of essential oil did not conform to the EP standard (10 mL kg(-1)). Variations in the essential oil composition of sage were studied using capillary gas chromatographic methods. A total of 40 components were identified. The principal components in the sage oils were 1,8-cineole, camphor, alpha-thujone, beta-thujone, borneol, and viridiflorol. The chemotypes of sage were not determined in investigated samples. The concentration of the main compounds in the drugs cultivated in Estonia varied in about the same range as the concentrations of these compounds in the oils of drugs obtained from other countries. The comparatively high concentration of toxic thujones seem to be characteristic to sage leaves cultivated in Estonia.
测定了在爱沙尼亚及其他欧洲国家生长的鼠尾草精油成分的差异。精油得率为2.2 - 24.8 mL kg⁻¹。有三个样品的精油含量不符合欧洲药典标准（10 mL kg⁻¹）。采用毛细管气相色谱法研究了鼠尾草精油成分的差异。共鉴定出40种成分。鼠尾草精油的主要成分是1,8 - 桉叶素、樟脑、α - 侧柏酮、β - 侧柏酮、冰片和绿花白千层醇。在所研究的样品中未确定鼠尾草的化学类型。爱沙尼亚种植的药材中主要化合物的浓度变化范围与从其他国家获得的药材精油中这些化合物的浓度变化范围大致相同。爱沙尼亚种植的鼠尾草叶似乎具有相对较高浓度的有毒侧柏酮。
