Healy D L, Burger H G, Muller H K
Mol Cell Endocrinol. 1978 Jun;11(1):1-6. doi: 10.1016/0303-7207(78)90027-8.
Orthodox views for the origin of the high concentration of prolactin (PRL) present in amniotic fluid suggest it is derived from maternal or fetal serum. However, the data on which these conclusions are based can also be interpreted to indicate that this hormone may be a product of placental or periplacental tissues. Trophoblast or amnion do not appear to produce PRL, while PRL synthesis by decidua-chorion is suggested from experiments in the rhesus monkey and by in vitro incubation of human tissue. Production of PRL by an extrapituitary cell is not without precedent and would be a simple explanation for high amniotic fluid PRL concentrations. Moreover, decidual-chorionic PRL would be strategically placed to mediate local functions of this hormone such as osmoregulation and myometrial inhibition.
关于羊水催乳素（PRL）高浓度来源的传统观点认为，它源自母体或胎儿血清。然而，得出这些结论所依据的数据也可以解释为表明这种激素可能是胎盘或胎盘周围组织的产物。滋养层或羊膜似乎不产生PRL，而恒河猴实验和人体组织体外培养表明，蜕膜 - 绒毛膜可合成PRL。垂体外细胞产生PRL并非没有先例，这将是羊水PRL浓度高的一个简单解释。此外，蜕膜 - 绒毛膜PRL在调节该激素的局部功能（如渗透调节和子宫肌层抑制）方面具有重要作用。
