先天性巨细胞病毒感染与小鼠神经发病机制模型的研究进展。
Congenital cytomegalovirus infection and advances in murine models of neuropathogenesis.
机构信息
Department of Microbiology, Howard University College of Medicine, Washington, DC, 20059, USA.
Department of Microbiology, Howard University College of Medicine, Washington, DC, 20059, USA.
出版信息
Virol Sin. 2022 Apr;37(2):318-320. doi: 10.1016/j.virs.2022.04.007. Epub 2022 May 2.
Abstract
• Congenital human cytomegalovirus (CMV) infection causes severe neuropathogenesis. • Murine CMV failed to break through the placental barrier to transmit to fetus. • Zhou et al. established a novel mouse system to model congenital HCMV infection. • The mouse CMV system by Zhou et al can be used for drug screening.
摘要
• 先天性人类巨细胞病毒（CMV）感染可导致严重的神经病变。 • 鼠源 CMV 无法穿透胎盘屏障传播给胎儿。 • 周等人建立了一种新型的小鼠系统来模拟先天性 HCMV 感染。 • 周等人的小鼠 CMV 系统可用于药物筛选。
Zotero 插件