Pawin Benjaporn, Suksathan Ratchuporn, Puangpradab Ratchadawan, Rachkeeree Apinya, Kantadoung Kuttiga
Queen Sirikit Botanic Garden, The Botanical Garden Organization, Chiang Mai, Thailand.
Nat Prod Res. 2023 Oct-Nov;37(19):3352-3356. doi: 10.1080/14786419.2022.2071886. Epub 2022 May 4.
Five selected medicinal plants in the family Zingiberaceae, , and were collected from Thailand. HPLC was used to determine the content of phenolic compounds in their ethanolic extracts. The total phenolic contents and the total flavonoid contents of were found to be higher than that of the others. The antioxidant activity of the extracts was assayed by two methods, namely ABTS and DPPH assays using HPTLC and a microplate spectrophotometer. Anticholinesterase activity was screened by the Ellman method against acetylcholinesterase, the chief enzyme of Alzheimer's disease. The results showed mild acetylcholinesterase effects. The results indicated that these five ginger species, especially have the potential to be a good source of natural antioxidants and anticholinesterase agents that could be further applied in the pharmaceutical industry.
从泰国采集了姜科的五种选定药用植物, 、 和 。采用高效液相色谱法测定其乙醇提取物中酚类化合物的含量。发现 的总酚含量和总黄酮含量高于其他植物。通过两种方法测定提取物的抗氧化活性,即使用高效薄层色谱法和微孔板分光光度计的ABTS和DPPH测定法。通过埃尔曼法针对乙酰胆碱酯酶(阿尔茨海默病的主要酶)筛选抗胆碱酯酶活性。结果显示出轻微的乙酰胆碱酯酶作用。结果表明,这五种姜科植物,尤其是 ,有可能成为天然抗氧化剂和抗胆碱酯酶剂的良好来源,可进一步应用于制药行业。