查巴迪疟原虫与恶性疟原虫的核型比较：对一个含有在恶性疟原虫中高度重复序列的查巴迪疟原虫cDNA的分析。
Karyotype comparison between P. chabaudi and P. falciparum: analysis of a P. chabaudi cDNA containing sequences highly repetitive in P. falciparum.
作者信息
Langsley G, Sibilli L, Mattei D, Falanga P, Mercereau-Puijalon O
出版信息
Nucleic Acids Res. 1987 Mar 11;15(5):2203-11. doi: 10.1093/nar/15.5.2203.
The molecular karyotypes of P. chabaudi and P. falciparum have been compared by pulse field gradient electrophoresis. P. chabaudi has 3 extra chromosomes in the 750-2000 Kb range although the overall number appears to be 14 as is the case for P. falciparum. The chromosomal location of the rRNA genes has been determined for P. chabaudi together with that of a 24 Kd antigen gene. The corresponding cDNA 443 may code for a protein unusually rich in tyrosine and contains sequences highly repetitive in P. falciparum.
已通过脉冲场梯度电泳对查巴迪疟原虫和恶性疟原虫的分子核型进行了比较。查巴迪疟原虫在750 - 2000千碱基范围内有3条额外染色体，尽管其总数似乎为14条，与恶性疟原虫的情况相同。已确定了查巴迪疟原虫rRNA基因以及一个24千道尔顿抗原基因的染色体定位。相应的cDNA 443可能编码一种酪氨酸含量异常丰富的蛋白质，并含有在恶性疟原虫中高度重复的序列。
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