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埃塞俄比亚成年人未确诊高血压及相关因素:系统评价和荟萃分析。

Undiagnosed hypertension and associated factors among adults in ethiopia: a systematic review and meta-analysis.

机构信息

School of Public Health, College of Health Science and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.

School of Medicine, College of Health Science and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.

出版信息

BMC Cardiovasc Disord. 2023 May 27;23(1):278. doi: 10.1186/s12872-023-03300-0.

Abstract

BACKGROUND

Hypertension is a major public health problem, resulting in 10 million deaths annually. Undiagnosed hypertension affects more people than ever before. It is more likely to be linked to severe hypertension, which can lead to stroke, cardiovascular disease, and ischemic heart disease. Thus, this systematic review and meta-analysis aimed to synthesize the prevalence of undiagnosed hypertension and its associated factors in Ethiopia.

METHODS

Databases, such as Medline/PubMed, Google Scholar, Science Direct, AJOL, and the Cochrane Library, were systematically searched to find potential studies published until December 2022. A Microsoft Excel spreadsheet was used to enter the extracted data. The pooled prevalence of undiagnosed hypertension and its associated factors was estimated using a random effect model. I statistics and the Cochrane Q-test were used to assess statistical heterogeneity across the studies. Begg's and Egger's tests were performed to identify possible publication bias.

RESULTS

A total of ten articles with 5,782 study participants were included in this meta-analysis. In the random effects model, the pooled prevalence of undiagnosed hypertension was 18.26% (95% CI = 14.94-21.58). Being older (OR = 3.8, 95% CI = 2.56, 5.66), having a body mass index > 25 kg/m2 (OR = 2.71, 95% CI = 2.1, 3.53), having a family history of hypertension (OR = 2.22, 95% CI = 1.47, 3.36), and having DM comorbidity (OR = 2.44, 95% CI = 1.38, 4.32) were significantly associated with undiagnosed hypertension.

CONCLUSION

In this meta-analysis, the pooled prevalence of undiagnosed hypertension was found to be high in Ethiopia. Being older, having a BMI > 25 kg/m2, having a family history of hypertension, and having DM comorbidity were found to be risk factors for undiagnosed hypertension.

摘要

背景

高血压是一个主要的公共卫生问题,每年导致 1000 万人死亡。未确诊的高血压影响的人数比以往任何时候都多。它更有可能与严重的高血压有关,严重的高血压可导致中风、心血管疾病和缺血性心脏病。因此,本系统评价和荟萃分析旨在综合埃塞俄比亚未确诊高血压的患病率及其相关因素。

方法

系统检索了 Medline/PubMed、Google Scholar、Science Direct、AJOL 和 Cochrane Library 等数据库,以寻找截至 2022 年 12 月发表的潜在研究。使用 Microsoft Excel 电子表格输入提取的数据。使用随机效应模型估计未确诊高血压及其相关因素的合并患病率。使用 I 统计量和 Cochrane Q 检验评估研究之间的统计学异质性。进行 Begg 和 Egger 检验以确定可能存在的发表偏倚。

结果

本荟萃分析共纳入 10 篇文章,涉及 5782 名研究参与者。在随机效应模型中,未确诊高血压的合并患病率为 18.26%(95%CI=14.94-21.58)。年龄较大(OR=3.8,95%CI=2.56-5.66)、身体质量指数(BMI)>25kg/m2(OR=2.71,95%CI=2.1-3.53)、高血压家族史(OR=2.22,95%CI=1.47-3.36)和糖尿病合并症(OR=2.44,95%CI=1.38-4.32)与未确诊高血压显著相关。

结论

在本荟萃分析中,发现埃塞俄比亚未确诊高血压的患病率较高。年龄较大、BMI>25kg/m2、有高血压家族史和糖尿病合并症是未确诊高血压的危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cd8/10225092/8a7b2d46ced7/12872_2023_3300_Fig1_HTML.jpg

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