CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Research Center for Coastal Environmental Engineering Technology of Shandong Province, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, 266071, China.
Langmuir. 2022 May 17;38(19):5963-5967. doi: 10.1021/acs.langmuir.2c00935. Epub 2022 May 5.
Combating environmental pollution constantly requires new affinity tools to selectively recognize and sensitively detect them. Molecularly imprinted polymers (MIPs) are plastic antibodies that have exhibited great potential as recognition units in optical sensing platforms to monitor wide varieties of environmental pollutants, including ionic species, organic compounds, gases, and even manufactured nanoparticles. The construction, sensing strategies, and applications of molecular-imprinting-based optical sensors (MI-OSs) have been discussed in recent reviews, thus we deliberately set them aside. This Perspective elaborates on unanswered questions and main approaches being taken to address the challenges of MI-OS technologies, which have been less considered until now. Specifically, we highlight obscure technical aspects of MI-OS fabrication and validation that impact their practical applications and importantly offer conceivable solutions to related problems to bridge the research gap.
应对环境污染需要不断开发新的亲和工具来选择性识别和灵敏检测污染物。分子印迹聚合物（MIPs）是一种塑料抗体，作为光学传感平台中的识别单元，在监测包括离子物种、有机化合物、气体甚至人工纳米颗粒等各种环境污染物方面表现出巨大潜力。基于分子印迹的光学传感器（MI-OS）的构建、传感策略和应用已在最近的综述中进行了讨论，因此我们将其搁置一旁。本观点详细阐述了尚未解决的问题和主要方法，以解决 MI-OS 技术的挑战，这些问题直到现在才得到更多的考虑。具体来说，我们强调了 MI-OS 制造和验证中模糊的技术方面，这些方面影响了它们的实际应用，并为相关问题提供了可行的解决方案，以弥合研究差距。
