Siotos Charalampos, Grunvald Miles W, Damoulakis George, Becerra Adan Z, O'Donoghue Cristina M, Dorafshar Amir H, Shenaq Deana S
Division of Plastic and Reconstructive Surgery, Rush University Medical Center, Chicago, IL.
Department of Surgery, Rush University Medical Center, Chicago, IL.
Eplasty. 2022 Apr 12;22:e9. eCollection 2022.
Melanoma is the third most common skin cancer and the leading cause of skin cancer mortality. This study sought to investigate trends in melanoma incidence, mortality, and burden of disease.
The authors assessed the records of the Global Burden of Disease Study 2017 to extract information about the incidence, mortality, and disability adjusted life years (DALY) related to melanoma during 1990-2017 in the US and other countries based on their socio-demographic index (SDI).
Melanoma incidence in the US increased 1.6 times, although the difference was not statistically significant. For patients over the age of 60, the incidence was significantly increased by 1.72 to 164.6 times. Mortality was relatively stable during the study period; however, it was increased for patients over 65 years of age (range: 1.03 to 70 times), although not statistically significant. Mortality-to-incidence ratio was decreased, but the difference was not statistically significant. For patients over 75 years of age, DALYs were statistically significantly increased by 1.34 to 1.71 times.
This study highlights differences in melanoma incidence and mortality from 1990-2017. Physicians involved in melanoma care should be aware of these changes in order to anticipate care needs.
黑色素瘤是第三常见的皮肤癌，也是皮肤癌死亡的主要原因。本研究旨在调查黑色素瘤的发病率、死亡率和疾病负担趋势。
作者评估了《2017年全球疾病负担研究》的记录，以提取1990 - 2017年期间美国和其他国家基于社会人口指数（SDI）的与黑色素瘤相关的发病率、死亡率和伤残调整生命年（DALY）信息。
美国黑色素瘤发病率增加了1.6倍，尽管差异无统计学意义。对于60岁以上的患者，发病率显著增加了1.72至164.6倍。在研究期间死亡率相对稳定；然而，65岁以上患者的死亡率有所增加（范围：1.03至70倍），尽管差异无统计学意义。死亡率与发病率之比有所下降，但差异无统计学意义。对于75岁以上的患者，伤残调整生命年在统计学上显著增加了1.34至1.71倍。
本研究突出了1990 - 2017年黑色素瘤发病率和死亡率的差异。参与黑色素瘤治疗的医生应了解这些变化，以便预测治疗需求。
