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稀有放线菌的次生代谢产物:化学与生物活性

The secondary metabolites of rare actinomycetes: chemistry and bioactivity.

作者信息

Ding Ting, Yang Luo-Jie, Zhang Wei-Dong, Shen Yun-Heng

机构信息

State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry Shanghai 201203 China

Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine Shanghai 201203 China.

出版信息

RSC Adv. 2019 Jul 16;9(38):21964-21988. doi: 10.1039/c9ra03579f. eCollection 2019 Jul 11.

Abstract

Actinomycetes are outstanding and fascinating sources of potent bioactive compounds, particularly antibiotics. In recent years, rare actinomycetes have had an increasingly important position in the discovery of antibacterial compounds, especially , and . Focusing on the period from 2008 to 2018, we herein summarize the structures and bioactivities of secondary metabolites from rare actinomycetes, involving 21 genera.

摘要

放线菌是强效生物活性化合物,尤其是抗生素的杰出且迷人的来源。近年来,稀有放线菌在抗菌化合物的发现中占据着越来越重要的地位,尤其是[此处原文缺失具体菌属名称]、[此处原文缺失具体菌属名称]和[此处原文缺失具体菌属名称]。本文聚焦于2008年至2018年期间,总结了来自21个属的稀有放线菌次生代谢产物的结构和生物活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21c9/9067109/bb447d738158/c9ra03579f-f1.jpg

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