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钙拮抗剂在大鼠实验性鼓室硬化中的意义。

The significance of calcium antagonists in rat experimental tympanosclerosis.

作者信息

Mann W, Beck C, Schaefer H E

出版信息

Arch Otorhinolaryngol. 1987;243(6):382-6. doi: 10.1007/BF00464647.

DOI:10.1007/BF00464647
PMID:3551898
Abstract

The effect of calcium antagonists in experimental tympanosclerosis following infection with Streptococcus pyogenes and vitamin D3 intoxication has been analyzed in a rat animal model. Compared with untreated animals, calcium antagonists exert a positive effect on the degenerative process and on secondary calcification in the subepithelial layer. This effect could be substantiated planimetrically.

摘要

在大鼠动物模型中，分析了钙拮抗剂对感染化脓性链球菌和维生素D3中毒后实验性鼓室硬化的影响。与未治疗的动物相比，钙拮抗剂对上皮下层的退行性病变过程和继发性钙化具有积极作用。这种作用可以通过平面测量得到证实。

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引用本文的文献

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Eur Arch Otorhinolaryngol. 2008 Apr;265(4):409-13. doi: 10.1007/s00405-007-0511-x. Epub 2007 Oct 25.
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Otomicroscopic and histologic findings of induced myringosclerosis in rats: a critical study of an experimental model.大鼠诱导性鼓膜硬化的耳显微镜和组织学研究：一种实验模型的批判性研究
Braz J Otorhinolaryngol. 2005 Sep-Oct;71(5):668-74. doi: 10.1016/s1808-8694(15)31272-6. Epub 2006 Mar 31.
3
Alteration of loosely bound calcium in the guinea pig organ of Corti after treatment with diltiazem as calcium channel blocker.

本文引用的文献

1
The role of matrix vesicles in the pathogenesis of tympanosclerosis.基质小泡在鼓室硬化症发病机制中的作用。
Acta Otolaryngol. 1980 Jan-Feb;89(1-2):43-52. doi: 10.3109/00016488009127107.
2
Tympanosclerosis of the ear drum. A scanning electronmicroscopic study.
Acta Otolaryngol. 1981 Mar-Apr;91(3-4):215-21.
3
Tympanosclerosis. An electron microscopic study of matrix vesicles.鼓室硬化症。基质小泡的电子显微镜研究。
Ann Otol Rhinol Laryngol Suppl. 1980 May-Jun;89(3 Pt 2):241-5. doi: 10.1177/00034894800890s356.
Eur Arch Otorhinolaryngol. 1997;254(5):223-9. doi: 10.1007/BF00874093.
4
Ultrastructural localization of Ca2(+)-binding sites in the middle ear mucosa of the rat.大鼠中耳黏膜中钙离子结合位点的超微结构定位
Eur Arch Otorhinolaryngol. 1990;247(3):156-60. doi: 10.1007/BF00175968.
4
Spontaneous course of secretory otitis and changes of the eardrum.
Arch Otolaryngol. 1984 May;110(5):281-9. doi: 10.1001/archotol.1984.00800310005002.
5
A low-viscosity epoxy resin embedding medium for electron microscopy.一种用于电子显微镜的低粘度环氧树脂包埋介质。
J Ultrastruct Res. 1969 Jan;26(1):31-43. doi: 10.1016/s0022-5320(69)90033-1.
6
Experimental tympanosclerosis following infection with Streptococcus pyogenes and vitamin D3 intoxication.感染化脓性链球菌及维生素D3中毒后的实验性鼓室硬化症
Arch Otorhinolaryngol. 1986;243(5):296-303. doi: 10.1007/BF00460205.
7
A unifying concept for the role of matrix vesicles and lysosomes in the formal pathogenesis of diseases of connective tissues and blood vessels.基质小泡和溶酶体在结缔组织和血管疾病的正式发病机制中的作用的统一概念。
Beitr Pathol. 1977 Apr;160(1):3-37. doi: 10.1016/s0005-8165(77)80003-6.