Gehrt Lise, Laake Ida, Englund Hélène, Nieminen Heta, Benn Christine Stabell, Feiring Berit, Trogstad Lill, Palmu Arto A, Sørup Signe
Bandim Health Project, Research Unit Open, Department of Clinical Research, University of Southern Denmark, Odense C, Denmark.
Research Center for Vitamins and Vaccines, Statens Serum Institut, Copenhagen, Denmark.
Clin Epidemiol. 2022 Apr 29;14:609-621. doi: 10.2147/CLEP.S355193. eCollection 2022.
Comparing rates of childhood infectious disease hospitalisations across countries may uncover areas for improvement in the prevention of severe childhood infections. We compared rates of childhood infectious disease hospital contacts across Denmark, Finland, Norway, and Sweden with the overall objective to elucidate potential differences in burden of disease and in organisational and registration practices.
Using national registries, we estimated incidence rates for infectious disease hospital contacts between 2008 and 2017 among children aged 0-14 years. We investigated the rates for different types of contacts (inpatient or outpatient including emergency room), duration of admission, and by sex.
During the study period, the rate of all hospital contacts per 1000 person-years was highest in Sweden (125.2) followed by Finland (87.1), Denmark (79.0), and Norway (62.1). The rates aligned for inpatient contacts with overnight stays; 19.3 (Denmark), 16.6 (Finland), 16.3 (Norway), and 13.0 (Sweden); these were highest in early infancy in all countries. A peak around 1 year of age was seen in all countries except in Sweden. The rates were higher among boys compared with girls in early childhood, after 13 years of age the rates among girls surpassed the boys.
Large cross-country differences were observed for outpatient and short-term hospital contacts for infectious diseases, affected by differences in organisational structures and coding practices across and within countries over time. Inpatient contacts requiring overnight stays reflected more comparable levels of severe infections across countries. Childhood infectious disease morbidity was greatest among boys and before 2 years of age.
比较各国儿童传染病住院率可能会发现预防儿童严重感染方面有待改进之处。我们比较了丹麦、芬兰、挪威和瑞典儿童传染病住院接触率,总体目标是阐明疾病负担以及组织和登记做法方面的潜在差异。
利用国家登记处的数据,我们估算了2008年至2017年期间0至14岁儿童传染病住院接触的发病率。我们调查了不同类型接触(住院或门诊包括急诊室)的发生率、住院时间以及性别差异。
在研究期间,每1000人年的所有住院接触率瑞典最高(125.2),其次是芬兰(87.1)、丹麦(79.0)和挪威(62.1)。过夜住院接触率的排名与之相符;丹麦为19.3,芬兰为16.6,挪威为16.3,瑞典为13.0;所有国家在婴儿早期这些比率最高。除瑞典外,所有国家在1岁左右出现一个峰值。幼儿期男孩的比率高于女孩,13岁以后女孩的比率超过男孩。
各国在传染病门诊和短期住院接触方面存在很大差异,这受到不同国家不同时期组织结构和编码做法差异的影响。需要过夜的住院接触反映出各国严重感染水平更具可比性。儿童传染病发病率在男孩中最高,且在2岁之前。