Robert Anne, Meunier Bernard
Laboratoire de Chimie de Coordination du CNRS, Inserm ERL 1289, 205 route de Narbonne, Toulouse 31077 Cedex, France.
School of Chemical Engineering and Light Industry, Guangdong University of Technology, Higher Education Mega Center, Guangzhou 510006, P.R. China.
ACS Nano. 2022 May 24;16(5):6956-6959. doi: 10.1021/acsnano.2c02966. Epub 2022 May 6.
Over the past 15 years, many articles have considered "nanozymes" as ferromagnetic nanoparticles having an "intrinsic peroxidase-like activity" in the presence of hydrogen peroxide. However, the definition and the catalytic activity of these nanozymes have been questioned. The present Perspective reports the main criteria that are essential to classify a nanoparticle as a nanozyme. It is important to consider that not all nanoparticles able to generate hydroxyl radicals in the presence of hydrogen peroxide without catalytic activity can be registered as nanozymes.
在过去的15年里，许多文章认为“纳米酶”是在过氧化氢存在下具有“内在过氧化物酶样活性”的铁磁性纳米颗粒。然而，这些纳米酶的定义和催化活性受到了质疑。本观点文章报道了将纳米颗粒归类为纳米酶所必需的主要标准。需要考虑的是，并非所有在过氧化氢存在下能够产生羟基自由基但无催化活性的纳米颗粒都能被登记为纳米酶。
