Urinary tract infections in pregnancy: Monuril single-dose treatment versus traditional therapy.

Today, it is widely accepted that a short-course or single-dose treatment with antimicrobial agents in pregnancy is the optimal therapy to minimize the risk of toxicity both for the mother and the fetus. A randomized trial comparing single-dose (3 g) treatment with fosfomycin trometamol (FT) versus pipemidic acid (200-gram doses b.i.d. for 7 days) in bacteriuric pregnant women is presented. The preliminary results show that single-dose FT has the same cure effect as conventional therapy with pipemidic acid.