De Cecco L, Ragni N
Eur Urol. 1987;13 Suppl 1:108-13. doi: 10.1159/000472874.
Today, it is widely accepted that a short-course or single-dose treatment with antimicrobial agents in pregnancy is the optimal therapy to minimize the risk of toxicity both for the mother and the fetus. A randomized trial comparing single-dose (3 g) treatment with fosfomycin trometamol (FT) versus pipemidic acid (200-gram doses b.i.d. for 7 days) in bacteriuric pregnant women is presented. The preliminary results show that single-dose FT has the same cure effect as conventional therapy with pipemidic acid.
如今，人们普遍认为，孕期使用抗菌药物进行短疗程或单剂量治疗是将母亲和胎儿的毒性风险降至最低的最佳疗法。本文介绍了一项针对菌尿症孕妇的随机试验，该试验比较了单剂量（3克）磷霉素氨丁三醇（FT）与吡哌酸（200毫克，每日两次，共7天）治疗的效果。初步结果表明，单剂量FT与吡哌酸传统疗法具有相同的治愈效果。
