由[具体发酵物]发酵的韩国白酒副产品具有美白肌肤的活性。 （你提供的原文中“by”后面缺少具体的发酵物信息，这里按补充完整的情况翻译了）
By-product of Korean liquor fermented by exhibits skin whitening activity.
作者信息
Jo Dong-Uk, Chin Young-Wook, Kim Yongeun, Kim Kyung-Tack, Kim Tae-Wan, Lim Tae-Gyu
机构信息
Department of Food Science & Biotechnology, Sejong University, Seoul, 05006 Republic of Korea.
Korea Food Research Institute, Wanju-gun, Jeollabuk-do 55365 Republic of Korea.
出版信息
Food Sci Biotechnol. 2022 Apr 11;31(5):587-596. doi: 10.1007/s10068-022-01062-7. eCollection 2022 May.
UNLABELLED
Herein, the skin whitening effect of the fermentation residue of was investigated. The fermentation residue showed radical scavenging activity and attenuated tyrosinase activity. Furthermore, the fermentation residue of significantly suppressed melanin generation in B16F10 cells. Interestingly, the sample-containing formulation exhibited increased skin whitening activity compared with that by the control formulation in a clinical study. Notably, the endogenous tyrosinase expression was not altered by the fermentation residue of ; however, the enzymatic activity of tyrosinase was inhibited. Furthermore, the sample did not change TRP1 and TRP2 expression in B16F10 cells. Thus, the fermentation residue of was assumed to directly suppress the tyrosinase enzyme. It was confirmed that the fermentation residue of was a competitive inhibitor of tyrosinase. Taken together, the fermentation residue of could be a novel skin whitening agent originating from the traditional Korean liquor production process.
SUPPLEMENTARY INFORMATION
The online version contains supplementary material available at 10.1007/s10068-022-01062-7.
未标记
本文研究了[具体物质]发酵残渣的美白效果。该发酵残渣具有自由基清除活性并减弱了酪氨酸酶活性。此外，[具体物质]的发酵残渣显著抑制了B16F10细胞中的黑色素生成。有趣的是，在一项临床研究中，含样品的配方与对照配方相比表现出增强的皮肤美白活性。值得注意的是，[具体物质]的发酵残渣未改变内源性酪氨酸酶的表达；然而，酪氨酸酶的酶活性受到了抑制。此外，该样品未改变B16F10细胞中TRP1和TRP2的表达。因此，推测[具体物质]的发酵残渣直接抑制了酪氨酸酶。证实了[具体物质]的发酵残渣是酪氨酸酶的竞争性抑制剂。综上所述，[具体物质]的发酵残渣可能是一种源自韩国传统酿酒工艺的新型皮肤美白剂。
补充信息
在线版本包含可在10.1007/s10068-022-01062-7获取的补充材料。
Zotero 插件