Glisan Sarah, Khan Nazim
Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USA.
University of Pittsburgh Medical Center Mercy, Pittsburgh, Pennsylvania, USA.
Case Rep Neurol. 2022 Mar 29;14(1):179-184. doi: 10.1159/000523707. eCollection 2022 Jan-Apr.
Bariatric surgery is used as a treatment for morbid obesity and often results in rapid weight loss. This procedure has been associated with postoperative nutritional deficiencies. Neurological complications due to nutritional deficiencies include Wernicke encephalopathy, a disorder that affects the central and peripheral nervous system due to thiamine (vitamin B1) deficiency. Wernicke encephalopathy can lead to irreversible consequences if not treated early. Here, we present a case of a 40-year-old woman that developed Wernicke encephalopathy 2 months after gastric bypass surgery, with additional findings of flat affect and concurrent polyradiculopathy. Her diagnosis was delayed due to unique symptoms and an initial workup with negative imaging findings, making the identification of this disorder more complex.
减肥手术被用作治疗病态肥胖的方法,且常常导致体重迅速下降。该手术与术后营养缺乏有关。营养缺乏引起的神经并发症包括韦尼克脑病,这是一种由于硫胺素(维生素B1)缺乏而影响中枢和周围神经系统的疾病。如果不及早治疗,韦尼克脑病会导致不可逆转的后果。在此,我们报告一例40岁女性病例,该患者在胃旁路手术后2个月发生韦尼克脑病,伴有情感平淡和并发多神经根病的其他表现。由于独特的症状和初始检查影像结果为阴性,她的诊断被延迟,使得这种疾病的识别更加复杂。