海港码头工人颊黏膜细胞的细胞遗传学生物监测
Cytogenetic Biomonitoring in Buccal Mucosa Cells from Seaport Dockers.
作者信息
Campos Katyane Negreiros, Alpire Maria Esther Suarez, Ribeiro Daniel Araki
机构信息
Department of Biosciences, Institute of Health and Society, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
出版信息
Cancer Diagn Progn. 2022 May 3;2(3):369-372. doi: 10.21873/cdp.10118. eCollection 2022 May-Jun.
BACKGROUND/AIM: Dockers of seaport working as stevedores are self-employed workers who carry out arduous and dangerous activities. To date, few studies have investigated the human health risks in these professionals. The aim of this study was to evaluate cytogenetic damage in oral cells of dockers of seaports working as stevedores by micronucleus assay in buccal cells.
PATIENTS AND METHODS
For this study, a total of 26 seaport dockers working as stevedores aged 51.2±8.4 years (all men) were included in this study. All volunteers had worked for at least 3 years. The control group consisted of 25 participants aged 55.2±9.9 years (all men), who did not work in the Port of Santos city.
RESULTS
The results showed statistically significant differences (p<0.05) of micronucleated cells in buccal mucosa cells of seaport dockers. Pyknosis, karyolysis and karrhyorexis did not show statistically significant differences (p>0.05) between groups.
CONCLUSION
The results of the present study suggest that seaport dockers present mutagenicity in oral cells.
背景/目的：海港码头从事装卸工作的码头工人是从事艰苦且危险活动的个体劳动者。迄今为止，很少有研究调查这些职业人群的健康风险。本研究的目的是通过颊细胞微核试验评估海港码头从事装卸工作的码头工人口腔细胞中的细胞遗传损伤。
患者与方法
本研究共纳入26名年龄为51.2±8.4岁（均为男性）的海港码头装卸工人。所有志愿者工作年限至少为3年。对照组由25名年龄为55.2±9.9岁（均为男性）、不在桑托斯市港口工作的参与者组成。
结果
结果显示，海港码头工人颊黏膜细胞中的微核细胞存在统计学显著差异（p<0.05）。固缩、核溶解和核碎裂在两组之间未显示出统计学显著差异（p>0.05）。
结论
本研究结果表明，海港码头工人的口腔细胞存在致突变性。
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