Ong Wei Ting Jess, Nyam Kar Lin
Department of Food Science and Nutrition, Faculty of Applied Sciences, UCSI University, 56000 Kuala Lumpur, Malaysia.
Saudi J Biol Sci. 2022 Apr;29(4):2085-2094. doi: 10.1016/j.sjbs.2022.01.035. Epub 2022 Jan 21.
Silver nanoparticles are well received in the cosmeceutical industry due to their broad spectrum of pharmacology applications. Research on the therapeutic properties exhibited by silver nanoparticles revealed that the antimicrobial and anti-inflammatory properties are the main attraction in the establishment of nanocosmeceutical products whereby their mechanisms of action are reviewed in this paper. In addition, studies on other uses of silver nanoparticles acknowledged that the particles act as antifungal agents in nail polishes and pigments in coloured beauty products such as lipsticks and eye shadows. Despite the extensive use of silver nanoparticles in the cosmetic line, there are still limited resources on the mechanism of actions and the effect of the particles on the bio-functionality of the body. The safety of silver nanoparticles could be comprehended from their skin penetration ability and toxicity to the human body in which it could be justified that both features are mainly influenced by the morphology of the particles and the method of application. This article summarizes exclusively on the synthesis of silver nanoparticles, the biomedical mechanisms and applications as well the limitations with respect to skin penetration ability and toxicity effects which will contribute significantly to the vast research on the association of nanotechnology and cosmetics.
由于银纳米颗粒具有广泛的药理学应用，它们在药妆行业中备受青睐。对银纳米颗粒所展现的治疗特性的研究表明，抗菌和抗炎特性是纳米药妆产品研发中的主要吸引力，本文将对其作用机制进行综述。此外，关于银纳米颗粒其他用途的研究承认，这些颗粒在指甲油中充当抗真菌剂，在口红和眼影等彩色美容产品中作为色素。尽管银纳米颗粒在化妆品领域有广泛应用，但关于其作用机制以及颗粒对人体生物功能影响的资源仍然有限。银纳米颗粒的安全性可以从其皮肤渗透能力和对人体的毒性来理解，有理由认为这两个特性主要受颗粒形态和应用方法的影响。本文专门总结了银纳米颗粒的合成、生物医学机制与应用，以及在皮肤渗透能力和毒性作用方面的局限性，这将对纳米技术与化妆品关联的大量研究做出重大贡献。
