Oh Jae-Young, Kim Jin-Soo, Lee Jung-Suck, Jeon You-Jin
Food Safety and Processing Research Division, National Institute of Fisheries Science, Busan, 46083 Republic of Korea.
Department of Seafood and Aquaculture Science/Institute of Marine Industry, Gyeongsang National University, Tongyeong, 53064 Korea.
J Food Sci Technol. 2022 May;59(5):2071-2079. doi: 10.1007/s13197-021-05221-2. Epub 2021 Aug 25.
Surimi is refined myofibrillar proteins of fish, which are materials of processed seafood products. However, the health-related outcomes associated with surimi consumption need further investigation. Given the high valued impact of surimi in the functional food industry, the study aims to evaluate its digest with regard to antioxidant potential to understand health benefits raised by surimi consumption. surimi digest (POSD) showed a significant DPPH and alkyl radical scavenging activity and protective effects against 2,20-azobis (2-methylpropionamidine) dihydrochloride (AAPH)-induced oxidative stressed Vero cells with a significant increasing cell viability and decreasing apoptosis. It also dramatically suppressed the production of reactive oxygen species and lipid peroxidation as well as prevented cell death and down-regulated pro-apoptotic genes at the mRNA levels in AAPH-stimulated zebrafish. This study reports the protective effects against oxidative stressed cells and zebrafish by a strong antioxidant activity of POSD. Therefore, surimi consumption could be a potential benefit in the prevention of oxidative stress-related diseases.
鱼糜是鱼类的精制肌原纤维蛋白，是加工海产品的原料。然而，与食用鱼糜相关的健康结果需要进一步研究。鉴于鱼糜在功能性食品工业中的高价值影响，本研究旨在评估其消化物的抗氧化潜力，以了解食用鱼糜所带来的健康益处。鱼糜消化物（POSD）表现出显著的1,1-二苯基-2-三硝基苯肼（DPPH）和烷基自由基清除活性，以及对2,2'-偶氮二异丁脒二盐酸盐（AAPH）诱导的氧化应激非洲绿猴肾细胞（Vero细胞）的保护作用，细胞活力显著增加，凋亡减少。它还显著抑制了活性氧的产生和脂质过氧化，以及在AAPH刺激的斑马鱼中预防细胞死亡并下调mRNA水平的促凋亡基因。本研究报告了POSD强大的抗氧化活性对氧化应激细胞和斑马鱼的保护作用。因此，食用鱼糜可能对预防氧化应激相关疾病有潜在益处。
