Sanchez Asley, Gandhi Kushal, Lee Ben, Garcia Jonathan Gomez, Ventolini Gary
Department of Obstetrics and Gynecology, School of Medicine, Texas Tech University Health Sciences Center (TTUHSC) at the Permian Basin, Odessa, TX, USA.
Department of Podiatry, California School of Podiatric Medicine, Samuel Merritt University, Oakland, CA, USA.
J Menopausal Med. 2022 Apr;28(1):42-45. doi: 10.6118/jmm.21032.
Lichen simplex chronicus commonly presents as a distressing vaginal lesion caused by severe, cyclical itch-scratch behavior. Lichen simplex chronicus is diagnosed by obtaining a detailed medical history, performing a physical exam, and recording of self-reported symptoms. Lichen simplex chronicus can be treated by corticosteroids, immunomodulators, antiepileptics, antihistamines, antidepressants, and phototherapy. Our case describes a 55-year-old female patient who presented to a clinic with recurrent vaginal itching, combined with compulsive scratching behavior that disrupted daily functioning. Physical examination revealed hypertrophic nodules located on the labia minora with scaling and hyperpigmentation. And the patient was diagnosed with lichen simplex chronicus. Empirical treatment with behavioral modifications and clobetasol propionate cream with an occlusive dressing produced significant improvements in symptoms at a six-month follow-up. Lichen simplex chronicus can have unusual presentations and; therefore, must be carefully differentiated from infectious and malignant skin lesions.
慢性单纯性苔藓通常表现为一种由严重的周期性瘙痒-搔抓行为引起的令人痛苦的阴道病变。通过获取详细的病史、进行体格检查以及记录自我报告的症状来诊断慢性单纯性苔藓。慢性单纯性苔藓可通过使用皮质类固醇、免疫调节剂、抗癫痫药、抗组胺药、抗抑郁药以及光疗进行治疗。我们的病例描述了一名55岁女性患者，她因反复出现阴道瘙痒并伴有强迫性搔抓行为而到诊所就诊，这种行为干扰了日常功能。体格检查发现小阴唇上有肥厚性结节，伴有脱屑和色素沉着。该患者被诊断为慢性单纯性苔藓。在六个月的随访中，通过行为矫正以及使用丙酸氯倍他索乳膏并加用封闭敷料进行经验性治疗，症状有了显著改善。慢性单纯性苔藓可能有不寻常的表现，因此，必须仔细与感染性和恶性皮肤病变相鉴别。
