铜中毒性巨细胞性肝炎
Giant Cell Hepatitis in Copper Toxicosis.
作者信息
Vij Mukul, Sankaranarayanan Srinivas, Sankaranarayanan Valavanur Subramanian, Manoharan Rakesh, Sundaram Sivanandam
机构信息
Department of Pathology, Dr Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chennai, India.
Pediatric Gastroenterology, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India.
出版信息
J Clin Exp Hepatol. 2022 Mar-Apr;12(2):719-720. doi: 10.1016/j.jceh.2021.07.006. Epub 2021 Jul 16.
Cholestatic jaundice in new born and infants results from biliary obstruction or hepatocellular dysfunction. Biliary atresia (BA) and Idiopathic neonatal hepatitis comprises the major aetiology. Cholestasis due to toxins is rare in infants. Indian childhood cirrhosis (ICC) and ICC like diseases have been described in infants. Herein, authors are describing a case of infantile cholestasis presenting at 4 months of age who was diagnosed to have copper related hepatotoxicosis on liver biopsy. Copper tumblers were used for preparation of formula milk that likely was the source of exogenous copper and the child improved well after removing the source of exogenous copper.
新生儿和婴儿的胆汁淤积性黄疸是由胆道梗阻或肝细胞功能障碍引起的。胆道闭锁（BA）和特发性新生儿肝炎是主要病因。婴儿因毒素导致的胆汁淤积很少见。婴儿期曾描述过印度儿童肝硬化（ICC）及类似ICC的疾病。在此，作者描述了一例4个月大出现婴儿胆汁淤积的病例，该患儿经肝活检诊断为与铜相关的肝中毒。曾使用铜杯制备配方奶，这可能是外源性铜的来源，去除外源性铜来源后患儿恢复良好。
Zotero 插件