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埃塞俄比亚亚的斯亚贝巴高血压患者抑郁程度及其相关因素:一项基于医院的横断面研究。

Magnitude and associated factors of depression among people with hypertension in Addis Ababa, Ethiopia: a hospital based cross-sectional study.

机构信息

School of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

BMC Psychiatry. 2022 May 10;22(1):327. doi: 10.1186/s12888-022-03972-6.

Abstract

BACKGROUND

The burden of depression is higher among people with chronic illnesses like hypertension and this comorbid condition leads to poor adherence to treatment and failure of compliance to lifestyle modifications, which in turn, increases risk of cardiovascular complications and mortalities. Low income countries, Ethiopia included, suffer from paucity of information describing the burden of hypertension comorbid with depression, which demands studies to narrow this knowledge gap, such as this one.

METHODS

Institution based cross-sectional study was conducted in three randomly selected public hospitals in Addis Ababa. Through a systematic random sampling method, a total of 416 known hypertensive patients with follow up in hypertension clinics with in the study period enrolled in the study. Data were collected through structured questionnaire administered by trained interviewer, which latter cleaned, edited and entered in to epi-data version 3.1. Descriptive and bi-variable and binary logistic regression analysis were done using the statistical software, SPSS version 25. Depression was assessed through Hospital Anxiety and Depression Scale (HADs).

RESULTS

The prevalence of depression among hypertensive patients was found to be 37.8% [95% CI (33.4%-42.5%)]. The binary logistic regression model revealed that, female sex [AOR = 5.37, 95% CI (3.089-9.35)], being married [AOR = 0.25, 95% CI (0.08-0.78)], presence of chronic comorbid illnesses [AOR = 3.03, 95% CI (1.78-5.16)], uncontrolled blood pressure [AOR = 2.80, 95% CI (1.65-4.75)], duration of hypertension of 5-10 years [AOR = 3.17, 95% CI (1.61-6.23)] and more than 10 years [AOR = 5.81, 95% CI (2.90-11.65)], family history of depression [AOR = 4.53, 95% CI (2.37-8.66)] and current alcohol consumption [AOR = 1.77, 95% CI (1.02-3.07)] were significantly associated with depression among hypertensive patients.

CONCLUSION

High proportion of depression was observed among hypertensive patients, and socio-demographic, clinical and behavioral characteristics were found to significantly influence the likelihood of occurrence. Health care providers should consider mental health status of hypertensive patients, and counsel for these factors.

摘要

背景

患有高血压等慢性病的人群抑郁负担更高,这种合并症会导致治疗依从性差,无法遵守生活方式改变,进而增加心血管并发症和死亡的风险。包括埃塞俄比亚在内的低收入国家缺乏描述高血压合并抑郁症负担的信息,这需要开展研究来缩小这一知识差距,就像本研究这样。

方法

这是一项在亚的斯亚贝巴的三家随机选择的公立医院进行的基于机构的横断面研究。通过系统随机抽样方法,共招募了 416 名在研究期间在高血压诊所接受随访的已知高血压患者。数据通过经过培训的访谈者进行的结构化问卷收集,后者对数据进行了清理、编辑并输入到 epi-data 版本 3.1 中。使用统计软件 SPSS 版本 25 进行描述性、双变量和二元逻辑回归分析。使用医院焦虑和抑郁量表 (HADs) 评估抑郁。

结果

高血压患者的抑郁患病率为 37.8% [95% CI (33.4%-42.5%)]。二元逻辑回归模型显示,女性 [AOR=5.37, 95% CI (3.089-9.35)]、已婚 [AOR=0.25, 95% CI (0.08-0.78)]、患有慢性合并症 [AOR=3.03, 95% CI (1.78-5.16)]、血压未控制 [AOR=2.80, 95% CI (1.65-4.75)]、高血压持续 5-10 年 [AOR=3.17, 95% CI (1.61-6.23)]和 10 年以上 [AOR=5.81, 95% CI (2.90-11.65)]、有抑郁家族史 [AOR=4.53, 95% CI (2.37-8.66)]和当前饮酒 [AOR=1.77, 95% CI (1.02-3.07)]与高血压患者的抑郁显著相关。

结论

高血压患者中观察到较高比例的抑郁,社会人口统计学、临床和行为特征被发现显著影响发生的可能性。医疗保健提供者应考虑高血压患者的心理健康状况,并针对这些因素进行咨询。

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