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埃塞俄比亚西南部吉马大学教学医院门诊心脏科成年心血管疾病患者抑郁障碍的影响因素:横断面研究

Determinates of depressive disorder among adult patients with cardiovascular disease at outpatient cardiac clinic Jimma University Teaching Hospital, South West Ethiopia: cross-sectional study.

作者信息

Umer Halima, Negash Alemayehu, Birkie Mengesha, Belete Asmare

机构信息

Research and Training Department of Amanuel Mental Specialized Hospital, Addis Abeba, Ethiopia.

2Department of Psychiatry, College of Public Health and Medical Sciences, Jimma University, Jimma, Ethiopia.

出版信息

Int J Ment Health Syst. 2019 Mar 5;13:13. doi: 10.1186/s13033-019-0269-8. eCollection 2019.

Abstract

BACKGROUND

Depression and heart disease are an important public-health problem. Depression is one of the most prevalent and disabling psychiatric disorders with more than three times increased risk among patients with cardiovascular disorders.

OBJECTIVE

To identify the prevalence and associated factors of depressive disorder among adult patients with cardiovascular disease.

METHODS

Institution based cross-sectional study design was used to conduct this study on 293 study participants attending an outpatient cardiac clinic at Jimma University Teaching Hospital. All eligible patients were recruited into the study consecutively. Depression was assessed using patient health questionnaire-9. The patient health questionnaire-9 had a total score of 27, from which 0-4: no/minimal depression, 5-9: mild depression, 10-14: moderately depression, 15-19: moderately severe depression and 20-27 severe depression. The data was feed into Epi-data version 3.1 and lastly exported to SPSS version 21 for analysis. Bivariate analysis was used to analyze the statistical association of covariates of interest with depressive disorder among patients with cardiovascular disease. Then, logistic regression analysis was used as a final model to control confounders. The strength of association was measured by a 95% confidence interval.

RESULTS

A total of 293 adult patients diagnosed with the cardiovascular disease were included in the study with 97% (n = 284) of response rate, 47.2% (n = 134) males and 52.8% (n = 150) females, making female to a male ratio around 1.1:1. The prevalence of depression was 52.8% (n = 150/284). Out of the subjects with depression 52.67% (n = 79), 36.0% (n = 54) and 11.33% (n = 17) were mild, moderate and severe depression, respectively. Variables such as employed, unemployed, physical activity, current cigarette user and poor social support were independently associated with depression in the final model.

CONCLUSIONS

In this study, depression was found to be highly prevalent psychiatric comorbidity in adult cardiovascular disease patients.

摘要

背景

抑郁症和心脏病是一个重要的公共卫生问题。抑郁症是最常见且使人致残的精神障碍之一,在心血管疾病患者中风险增加了三倍多。

目的

确定成年心血管疾病患者中抑郁症的患病率及相关因素。

方法

采用基于机构的横断面研究设计,对吉马大学教学医院门诊心脏科的293名研究参与者进行了这项研究。所有符合条件的患者均连续纳入研究。使用患者健康问卷-9评估抑郁症。患者健康问卷-9的总分是27分,其中0 - 4分表示无/轻度抑郁,5 - 9分表示轻度抑郁,10 - 14分表示中度抑郁,15 - 19分表示中度重度抑郁,20 - 27分表示重度抑郁。数据录入Epi - data 3.1版本,最后导出到SPSS 21版本进行分析。采用双变量分析来分析心血管疾病患者中感兴趣的协变量与抑郁症的统计关联。然后,使用逻辑回归分析作为最终模型来控制混杂因素。关联强度通过95%置信区间衡量。

结果

本研究共纳入293名诊断为心血管疾病的成年患者,应答率为97%(n = 284),男性47.2%(n = 134),女性52.8%(n = 150),男女比例约为1.1:1。抑郁症的患病率为52.8%(n = 150/284)。在抑郁症患者中,轻度、中度和重度抑郁分别占52.67%(n = 79)、36.0%(n = 54)和11.33%(n = 17)。在最终模型中,就业、失业、体育活动、当前吸烟者和社会支持差等变量与抑郁症独立相关。

结论

在本研究中发现,抑郁症在成年心血管疾病患者中是高度普遍的精神共病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d15d/6399879/b5f6e4df5db3/13033_2019_269_Fig1_HTML.jpg

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