STOP NCD PROJECT, Ghana College of Physicians and Surgeons, Accra, Ghana
Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.
BMJ Open. 2024 Nov 27;14(11):e081824. doi: 10.1136/bmjopen-2023-081824.
Mental illness remains a significant global health concern that affects diverse populations, including individuals living with hypertension and/or type 2 diabetes, predominantly in lower-income to middle-income countries. The association between non-communicable diseases (NCDs) and mental illness is firmly established globally, however, this connection has yet to be comprehensively explored in West Africa. Our systematic review and meta-analysis aim to synthesise existing evidence on the prevalence, incidence, and risk factors for comorbid mental illness with hypertension and/or type 2 diabetes in West Africa. This effort seeks to contribute to bridging the knowledge gap and facilitating the implementation of interventions tailored to this context.
A comprehensive search will be conducted across multiple databases (PubMed, Google Scholar, PsycINFO, Carin Info and CINAHL), supplemented by searches on the websites of the WHO and various countries' ministries of health, and references cited in relevant papers. Inclusion criteria specify studies conducted in countries from the Economic Community of West African States, reported from January 2000 until date of search, focusing on adults with hypertension and/or type 2 diabetes and mental illness. Exclusion criteria encompass studies outside the specified time frame, involving pregnant women, or lacking relevant outcomes. There will be no language restrictions for inclusion. Study selection, data extraction and risk of bias assessment will be carried out independently by at least two reviewers. We will employ pooled proportions of OR, risk ratio and mean differences to assess prevalence, and incidence of mental illness and heterogeneity will be assessed.
This protocol does not require ethical approval; however, it is a part of a larger study on NCDs, which has received ethical clearance from the Ghana Health Service (ID NO: GHS-ERC 013/02/23). The results will be presented to stakeholders (policymakers and practitioners) and disseminated through conferences and peer-reviewed publications.
CRD42023450732.
精神疾病仍然是一个重大的全球健康问题，影响着包括高血压和/或 2 型糖尿病患者在内的不同人群，这些患者主要分布在中低收入国家。非传染性疾病（NCDs）和精神疾病之间的关联在全球范围内已经得到了充分证实，然而，在西非，这一关联尚未得到全面探讨。我们的系统综述和荟萃分析旨在综合现有证据，探讨西非高血压和/或 2 型糖尿病患者合并精神疾病的患病率、发病率和危险因素。这项工作旨在为弥合知识差距和促进针对这一背景的干预措施的实施做出贡献。
我们将在多个数据库（PubMed、Google Scholar、PsycINFO、Carin Info 和 CINAHL）中进行全面搜索，并补充世界卫生组织（WHO）和各国卫生部网站以及相关论文参考文献的搜索。纳入标准规定研究对象为来自西非国家经济共同体的国家，研究时间为 2000 年 1 月至搜索日期，研究重点为高血压和/或 2 型糖尿病合并精神疾病的成年人。排除标准包括不在规定时间范围内的研究、涉及孕妇的研究或缺乏相关结局的研究。纳入研究不设语言限制。研究选择、数据提取和偏倚风险评估将由至少两名评审员独立进行。我们将采用 OR、风险比和均数差的汇总比例来评估精神疾病的患病率和发病率，并评估异质性。
本方案不需要伦理批准；然而，它是一项关于非传染性疾病的更大研究的一部分，该研究已获得加纳卫生局的伦理批准（ID 号：GHS-ERC 013/02/23）。研究结果将提交给利益相关者（决策者和实践者），并通过会议和同行评议出版物进行传播。
PROSPERO 注册号：CRD42023450732。
