外泌体miR-26a-5p的缺失促进子宫内膜癌淋巴管生成和淋巴转移。 - Suppr | 超能文献

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Loss of exosomal miR-26a-5p contributes to endometrial cancer lymphangiogenesis and lymphatic metastasis.

作者信息

Wang Jing, Gong Xiaodi, Yang Linlin, Li Lijuan, Gao Xiaoyan, Ni Ting, Yang Xiaoming, Fan Qiong, Sun Xiao, Wang Yudong

机构信息

Department of Gynecologic Oncology, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Shanghai Municipal Key Clinical Specialty, Shanghai, China.

出版信息

Clin Transl Med. 2022 May;12(5):e846. doi: 10.1002/ctm2.846.

DOI:10.1002/ctm2.846

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9092006/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dc/9092006/8dca7e2f8f00/CTM2-12-e846-g001.jpg

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dc/9092006/3fa2412dd2ea/CTM2-12-e846-g004.jpg

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dc/9092006/6c658390be16/CTM2-12-e846-g002.jpg

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dc/9092006/1dd5896a3ce9/CTM2-12-e846-g003.jpg

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dc/9092006/8dca7e2f8f00/CTM2-12-e846-g001.jpg

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dc/9092006/3fa2412dd2ea/CTM2-12-e846-g004.jpg

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dc/9092006/6c658390be16/CTM2-12-e846-g002.jpg

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dc/9092006/1dd5896a3ce9/CTM2-12-e846-g003.jpg

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29dc/9092006/8dca7e2f8f00/CTM2-12-e846-g001.jpg

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CA Cancer J Clin. 2022 Jan;72(1):7-33. doi: 10.3322/caac.21708. Epub 2022 Jan 12.

2

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J Clin Invest. 2020 Jan 2;130(1):404-421. doi: 10.1172/JCI130892.

3

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Biomedicines. 2024 Jul 4;12(7):1477. doi: 10.3390/biomedicines12071477.

4

The systematic role of pancreatic cancer exosomes: distant communication, liquid biopsy and future therapy.胰腺癌外泌体的系统性作用：远程通讯、液体活检与未来治疗

Cancer Cell Int. 2024 Jul 25;24(1):264. doi: 10.1186/s12935-024-03456-5.

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Technol Cancer Res Treat. 2023 Jan-Dec;22:15330338231198348. doi: 10.1177/15330338231198348.

6

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