Hamama Wafaa S, Ibrahim Mona E, Gooda Ayaa A, Zoorob Hanafi H
Department of Chemistry, Faculty of Science, Mansoura University El-Gomhoria Street Mansoura 35516 Egypt
RSC Adv. 2018 Feb 23;8(16):8484-8515. doi: 10.1039/c7ra11537g.
This review highlights the recently cited research data in the literature on the chemistry of 2-chloroquinoline-3-carbaldehyde and related analogs and their applications over the period from 2013 to 2017. It covers: synthesis of quinoline ring systems and reactions adopted to construct fused or binary quinoline-cord heterocyclic systems. The biological evaluation and the synthetic applications of the target compounds were illustrated.
本综述重点介绍了2013年至2017年期间文献中最近引用的关于2-氯喹啉-3-甲醛及其相关类似物的化学研究数据及其应用。内容包括:喹啉环系统的合成以及构建稠合或二元喹啉-稠杂环系统所采用的反应。文中还阐述了目标化合物的生物学评价和合成应用。