• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

流行病学的线性动力学视角:新冠疫情早期爆发与人员流动之间的相互作用

A linear dynamical perspective on epidemiology: interplay between early COVID-19 outbreak and human mobility.

作者信息

Mustavee Shakib, Agarwal Shaurya, Enyioha Chinwendu, Das Suddhasattwa

机构信息

Department of Civil Engineering, University of Central Florida, Orlando, FL 32816 USA.

Department of Electrical and Computer Engineering, University of Central Florida, Orlando, FL 32816 USA.

出版信息

Nonlinear Dyn. 2022;109(2):1233-1252. doi: 10.1007/s11071-022-07469-5. Epub 2022 May 5.

DOI:10.1007/s11071-022-07469-5
PMID:35540628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9070110/
Abstract

This paper investigates the impact of human activity and mobility (HAM) in the spreading dynamics of an epidemic. Specifically, it explores the interconnections between HAM and its effect on the early spread of the COVID-19 virus. During the early stages of the pandemic, effective reproduction numbers exhibited a high correlation with human mobility patterns, leading to a hypothesis that the HAM system can be studied as a coupled system with disease spread dynamics. This study applies the generalized Koopman framework with control inputs to determine the nonlinear disease spread dynamics and the input-output characteristics as a locally linear controlled dynamical system. The approach solely relies on the snapshots of spatiotemporal data and does not require any knowledge of the system's underlying physical laws. We exploit the Koopman operator framework by utilizing the Hankel dynamic mode decomposition with Control (HDMDc) algorithm to obtain a linear disease spread model incorporating human mobility as a control input. The study demonstrated that the proposed methodology could capture the impact of local mobility on the early dynamics of the ongoing global pandemic. The obtained locally linear model can accurately forecast the number of new infections for various prediction windows ranging from two to four weeks. The study corroborates a leader-follower relationship between mobility and disease spread dynamics. In addition, the effect of delay embedding in the HDMDc algorithm is also investigated and reported. A case study was performed using COVID infection data from Florida, US, and HAM data extracted from

摘要

本文研究了人类活动与流动性(HAM)在传染病传播动态中的影响。具体而言,它探讨了HAM及其对COVID-19病毒早期传播的影响之间的相互联系。在疫情早期阶段,有效繁殖数与人类流动模式呈现出高度相关性,从而引出了一个假设,即HAM系统可作为一个与疾病传播动态耦合的系统进行研究。本研究应用带有控制输入的广义库普曼框架来确定非线性疾病传播动态以及作为局部线性受控动态系统的输入-输出特性。该方法仅依赖于时空数据的快照,无需任何关于系统潜在物理规律的知识。我们通过利用带控制的汉克尔动态模式分解(HDMDc)算法来利用库普曼算子框架,以获得一个将人类流动作为控制输入纳入的线性疾病传播模型。研究表明,所提出的方法能够捕捉局部流动性对当前全球大流行早期动态的影响。所获得的局部线性模型能够准确预测从两周到四周不等的各种预测窗口内的新增感染病例数。该研究证实了流动性与疾病传播动态之间的主从关系。此外,还研究并报告了HDMDc算法中延迟嵌入的影响。使用来自美国佛罗里达州的COVID感染数据以及从……提取的HAM数据进行了案例研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/2a3d9cf4ad6a/11071_2022_7469_Fig17_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/babc3ba40ea3/11071_2022_7469_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/51ad173b19e7/11071_2022_7469_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/c7fc381c4688/11071_2022_7469_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/5ae38203d99c/11071_2022_7469_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/b9b3cf7c4606/11071_2022_7469_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/fc48da5c9110/11071_2022_7469_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/ddae358e8460/11071_2022_7469_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/d8b4ff8ef598/11071_2022_7469_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/634fd7921e62/11071_2022_7469_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/4e66a4caadc2/11071_2022_7469_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/c3c688832d97/11071_2022_7469_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/e0f3a7dd5f14/11071_2022_7469_Fig12_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/e3637db01d0e/11071_2022_7469_Fig13_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/eb2e878ec485/11071_2022_7469_Fig14_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/d9f65e55358c/11071_2022_7469_Fig15_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/36d18cd68a13/11071_2022_7469_Fig16_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/2a3d9cf4ad6a/11071_2022_7469_Fig17_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/babc3ba40ea3/11071_2022_7469_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/51ad173b19e7/11071_2022_7469_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/c7fc381c4688/11071_2022_7469_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/5ae38203d99c/11071_2022_7469_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/b9b3cf7c4606/11071_2022_7469_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/fc48da5c9110/11071_2022_7469_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/ddae358e8460/11071_2022_7469_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/d8b4ff8ef598/11071_2022_7469_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/634fd7921e62/11071_2022_7469_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/4e66a4caadc2/11071_2022_7469_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/c3c688832d97/11071_2022_7469_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/e0f3a7dd5f14/11071_2022_7469_Fig12_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/e3637db01d0e/11071_2022_7469_Fig13_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/eb2e878ec485/11071_2022_7469_Fig14_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/d9f65e55358c/11071_2022_7469_Fig15_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/36d18cd68a13/11071_2022_7469_Fig16_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c763/9070110/2a3d9cf4ad6a/11071_2022_7469_Fig17_HTML.jpg

相似文献

1
A linear dynamical perspective on epidemiology: interplay between early COVID-19 outbreak and human mobility.流行病学的线性动力学视角:新冠疫情早期爆发与人员流动之间的相互作用
Nonlinear Dyn. 2022;109(2):1233-1252. doi: 10.1007/s11071-022-07469-5. Epub 2022 May 5.
2
Koopman Invariant Subspaces and Finite Linear Representations of Nonlinear Dynamical Systems for Control.用于控制的非线性动力系统的库普曼不变子空间和有限线性表示
PLoS One. 2016 Feb 26;11(2):e0150171. doi: 10.1371/journal.pone.0150171. eCollection 2016.
3
Generalizing Koopman Theory to Allow for Inputs and Control.将库普曼理论进行推广以纳入输入和控制因素。
SIAM J Appl Dyn Syst. 2018;17(1):909-930. doi: 10.1137/16M1062296. Epub 2018 Mar 27.
4
Subspace dynamic mode decomposition for stochastic Koopman analysis.子空间动态模态分解的随机 Koopman 分析。
Phys Rev E. 2017 Sep;96(3-1):033310. doi: 10.1103/PhysRevE.96.033310. Epub 2017 Sep 18.
5
Data-driven fault detection and isolation of nonlinear systems using deep learning for Koopman operator.基于深度学习的库普曼算子对非线性系统进行数据驱动的故障检测与隔离
ISA Trans. 2023 Mar;134:200-211. doi: 10.1016/j.isatra.2022.08.030. Epub 2022 Sep 5.
6
A Koopman operator-based prediction algorithm and its application to COVID-19 pandemic and influenza cases.基于 Koopman 算子的预测算法及其在 COVID-19 大流行和流感病例中的应用。
Sci Rep. 2024 Mar 9;14(1):5788. doi: 10.1038/s41598-024-55798-9.
7
Koopman operator and its approximations for systems with symmetries.具有对称的系统的 Koopman 算子及其逼近。
Chaos. 2019 Sep;29(9):093128. doi: 10.1063/1.5099091.
8
Extended Dynamic Mode Decomposition with Invertible Dictionary Learning.基于可反演字典学习的扩展动态模态分解。
Neural Netw. 2024 May;173:106177. doi: 10.1016/j.neunet.2024.106177. Epub 2024 Feb 15.
9
Two methods to approximate the Koopman operator with a reservoir computer.用回声状态网络逼近库普曼算子的两种方法。
Chaos. 2021 Feb;31(2):023116. doi: 10.1063/5.0026380.
10
Koopman-Based MPC With Learned Dynamics: Hierarchical Neural Network Approach.基于库普曼模型的带学习动力学的模型预测控制:分层神经网络方法
IEEE Trans Neural Netw Learn Syst. 2024 Mar;35(3):3630-3639. doi: 10.1109/TNNLS.2022.3194958. Epub 2024 Feb 29.

引用本文的文献

1
Dynamic Patterns and Modeling of Early COVID-19 Transmission by Dynamic Mode Decomposition.基于动态模式分解的 COVID-19 早期传播的动态模式与建模。
Prev Chronic Dis. 2023 Oct 26;20:E95. doi: 10.5888/pcd20.230089.

本文引用的文献

1
Application of non-parametric models for analyzing survival data of COVID-19 patients.应用非参数模型分析 COVID-19 患者的生存数据。
J Infect Public Health. 2021 Oct;14(10):1328-1333. doi: 10.1016/j.jiph.2021.08.025. Epub 2021 Aug 27.
2
Spatial-Temporal Relationship Between Population Mobility and COVID-19 Outbreaks in South Carolina: Time Series Forecasting Analysis.南卡罗来纳州人口流动与 COVID-19 疫情爆发的时空关系:时间序列预测分析。
J Med Internet Res. 2021 Apr 13;23(4):e27045. doi: 10.2196/27045.
3
Exploring the influence of human mobility factors and spread prediction on early COVID-19 in the USA.
探究人类流动性因素和传播预测对美国早期 COVID-19 的影响。
BMC Public Health. 2021 Mar 29;21(1):615. doi: 10.1186/s12889-021-10682-3.
4
A review on COVID-19 forecasting models.关于新冠病毒疾病预测模型的综述。
Neural Comput Appl. 2021 Feb 4:1-11. doi: 10.1007/s00521-020-05626-8.
5
The Use and Misuse of Mathematical Modeling for Infectious Disease Policymaking: Lessons for the COVID-19 Pandemic.数学模型在传染病决策中的应用与误用:对 COVID-19 大流行的教训。
Med Decis Making. 2021 May;41(4):379-385. doi: 10.1177/0272989X21990391. Epub 2021 Feb 3.
6
A big-data driven approach to analyzing and modeling human mobility trend under non-pharmaceutical interventions during COVID-19 pandemic.一种大数据驱动的方法,用于分析和建模新冠疫情期间非药物干预下的人类流动趋势。
Transp Res Part C Emerg Technol. 2021 Mar;124:102955. doi: 10.1016/j.trc.2020.102955. Epub 2021 Jan 9.
7
Global and local mobility as a barometer for COVID-19 dynamics.全球和本地流动性作为 COVID-19 动态的晴雨表。
Biomech Model Mechanobiol. 2021 Apr;20(2):651-669. doi: 10.1007/s10237-020-01408-2. Epub 2021 Jan 15.
8
Modelling the role of optimal social distancing on disease prevalence of COVID-19 epidemic.模拟最佳社交距离对新冠疫情疾病流行率的作用。
Int J Dyn Control. 2021;9(3):1053-1077. doi: 10.1007/s40435-020-00721-z. Epub 2020 Nov 9.
9
Human mobility trends during the early stage of the COVID-19 pandemic in the United States.美国 COVID-19 大流行早期的人口流动趋势。
PLoS One. 2020 Nov 9;15(11):e0241468. doi: 10.1371/journal.pone.0241468. eCollection 2020.
10
Using a partial differential equation with Google Mobility data to predict COVID-19 in Arizona.利用带有谷歌流动性数据的偏微分方程预测亚利桑那州的 COVID-19 疫情。
Math Biosci Eng. 2020 Jul 13;17(5):4891-4904. doi: 10.3934/mbe.2020266.