Wu Yan, Bi Su-Xia, Huang Zhen, Qi Jin, Yu Bo-Yang
Jiangsu Key Laboratory of TCM Evaluation and Translational Research, China Pharmaceutical University Nanjing 211198 People's Republic of China
RSC Adv. 2018 Jan 11;8(5):2498-2505. doi: 10.1039/c7ra12363a. eCollection 2018 Jan 9.
Six new steroidal saponins (1-6) and one known steroidal saponin (7) were obtained from the roots of (L. f.) Ker-Gawl. Their structures were determined by the detailed analysis of extensive nuclear magnetic resonance and mass spectroscopic data. The cytotoxic activities of these compounds against MDA-MB-435, HepG2 and A549 cell lines were also investigated.
从(L. f.)Ker-Gawl.的根中获得了6种新的甾体皂苷(1-6)和1种已知的甾体皂苷(7)。通过对大量核磁共振和质谱数据的详细分析确定了它们的结构。还研究了这些化合物对MDA-MB-435、HepG2和A549细胞系的细胞毒性活性。