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使用含植物提取物的洗发水和摩丝治疗18只犬特发性慢性脂溢性皮炎方案的疗效和耐受性

Performance and Tolerance of a Protocol for Idiopathic Chronic Greasy Seborrhea in 18 Dogs Using a Shampoo and Mousse Containing Plant Extracts.

作者信息

Kondratjeva Jevgenija, Brun Jessie, Amalric Nicolas, Moog Fabien, Combarros Daniel, Pressanti Charline, Zemirline Claudine, Maubert Nadège, Ollivier Elodie, Gatellet Marina, Cadiergues Marie Christine

机构信息

Small Animal Clinic, Université de Toulouse, ENVT, 31076 Toulouse, France.

QIMA Life Sciences, 31670 Labège, France.

出版信息

Vet Sci. 2023 Jan 28;10(2):95. doi: 10.3390/vetsci10020095.

Abstract

The study aimed to evaluate the tolerance, performance and effect on hair lipids and skin hydration of a protocol combining applications of one shampoo and subsequent mousses containing plant extracts (Ophytrium and Seboliance) in dogs with an undiagnosed chronic greasy keratinisation disorder. Six dogs were washed with plain water on day (D)0. Twelve dogs were shampooed on D0 and received eight mousse applications at 48-72 h intervals from D2 to D18. Clinical score (CS), Natural Moisturizing Factors (NMF) and hair lipids (HL) were evaluated on D0, D0 + 4 h, D7, D14 and D24. At baseline, no significant differences were observed in CS, NMF and HL between groups. In the control group, CS and HL remained stable throughout the study while a slight decrease in NMF was observed at D0 + 4 h. CS was significantly reduced in the test group between D0 and D7 (-53%) which reached 91% at D24 ( < 0.05), with no side effects. NMF levels decreased in the test group at D0 + 4 h (-73%, < 0.0001) and returned to baseline from D14. In conclusion, one shampoo and subsequent mousse applications rapidly and safely improved coat quality in dogs with an undiagnosed keratinisation disorder without affecting NMF and HL contents over the study period.

摘要

本研究旨在评估一种方案对患有未确诊慢性油腻性角质化疾病的犬类毛发脂质和皮肤水合作用的耐受性、效果及影响,该方案包括先用一种洗发水清洗,随后使用含植物提取物(Ophytrium和Seboliance)的慕斯。6只犬在第0天(D0)用清水清洗。12只犬在D0接受洗发水清洗,并在从D2到D18期间每隔48 - 72小时接受8次慕斯涂抹。在D0、D0 + 4小时、D7、D14和D24评估临床评分(CS)、天然保湿因子(NMF)和毛发脂质(HL)。在基线时,两组之间在CS、NMF和HL方面未观察到显著差异。在对照组中,CS和HL在整个研究过程中保持稳定,而在D0 + 4小时观察到NMF略有下降。在试验组中,CS在D0至D7之间显著降低(-53%),在D24时降至91%(<0.05),且无副作用。试验组中NMF水平在D0 + 4小时下降(-73%,<0.0001),并从D14恢复到基线水平。总之,一种洗发水及随后的慕斯涂抹能快速且安全地改善患有未确诊角质化疾病犬类的被毛质量,且在研究期间不影响NMF和HL含量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36fa/9960626/757a8beace11/vetsci-10-00095-g001.jpg

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