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深共熔溶剂催化苯并恶唑与芳香醛的芳基化反应

Deep eutectic solvent-catalyzed arylation of benzoxazoles with aromatic aldehydes.

作者信息

Tran Phuong Hoang, Thi Hang Anh-Hung

机构信息

Department of Organic Chemistry, Faculty of Chemistry, University of Science, Viet Nam National University Ho Chi Minh City 721337 Viet Nam

出版信息

RSC Adv. 2018 Mar 20;8(20):11127-11133. doi: 10.1039/c8ra01094c. eCollection 2018 Mar 16.

Abstract

A novel and efficient methodology for the arylation of benzoxazoles with aromatic aldehydes catalyzed by deep eutectic solvent has been developed. The reaction smoothly proceeded with a wide range of substrates to give the desired products in high yields within short reaction time. Deep eutectic solvents are easily recovered and reused without significant loss of catalytic activity.

摘要

已开发出一种新颖且高效的方法,用于在深共熔溶剂催化下使苯并恶唑与芳香醛进行芳基化反应。该反应能顺利地与多种底物进行,在短反应时间内以高收率得到所需产物。深共熔溶剂易于回收和重复使用,且催化活性不会有显著损失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/861d/9078944/79c37e208e84/c8ra01094c-f1.jpg

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