Zhang Xinhe, Guan Lin, Tian Haoyu, Li Yiling
Gastroenterology Department, The First Affiliated Hospital of China Medical University, Shenyang, China.
The Third Clinical Department, China Medical University, Shenyang, China.
Front Med (Lausanne). 2022 Apr 25;9:865458. doi: 10.3389/fmed.2022.865458. eCollection 2022.
To investigate the incidence and risk factors of gallbladder stones and polyps in individuals undergoing physical examinations in Liaoning province, China.
This is a retrospective study of adults who underwent routine health examinations at Xikang Medical Center in Liaoning Province (Shenyang, Dandong, and Dalian) from 01/2016 to 12/2020. The routine health examination included anthropometry, blood tests, and liver ultrasound. Based on liver ultrasound results, patients were grouped into those with gallbladder stones, those with gallbladder polyps, those with both stones and polyps, and those with neither.
Of the 284,129 included subjects, 6,537 (2.30%) were diagnosed with gallbladder stones, and 18,873 (6.64%) were diagnosed with gallbladder polyps. The overall prevalence in Liaoning province increased each year, peaking in 2020. The prevalence of gallbladder stones was higher among females than males (2.39% vs. 2.23%, respectively), while the prevalence of gallbladder polyps was higher among males. The gallbladder polyp group had higher BMI, FBG, SBP, DBP, TG, TC, LDL-C, HDL-C, AST, ALP, GGT, BUN, Scr, SUA. Except for HDL-C, all factors were also higher in the gallbladder stone group. Patients with fatty liver had a higher prevalence of gallbladder stones and polyps than participants without fatty liver.
The prevalence of gallbladder stones and polyps in Liaoning varies by sex, economic status of the city of residence, BMI, and metabolic indicators.
调查中国辽宁省接受体检人群中胆囊结石和息肉的发病率及危险因素。
这是一项对2016年1月至2020年12月在辽宁省（沈阳、丹东和大连）西康医疗中心接受常规健康检查的成年人进行的回顾性研究。常规健康检查包括人体测量、血液检查和肝脏超声检查。根据肝脏超声检查结果，将患者分为胆囊结石患者、胆囊息肉患者、结石和息肉均有的患者以及两者均无的患者。
在纳入的284,129名受试者中，6537名（2.30%）被诊断为胆囊结石，18873名（6.64%）被诊断为胆囊息肉。辽宁省的总体患病率逐年上升，在2020年达到峰值。胆囊结石的患病率女性高于男性（分别为2.39%和2.23%），而胆囊息肉的患病率男性更高。胆囊息肉组的BMI、空腹血糖（FBG）、收缩压（SBP）、舒张压（DBP）、甘油三酯（TG）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）、谷草转氨酶（AST）、碱性磷酸酶（ALP）、γ-谷氨酰转肽酶（GGT）、尿素氮（BUN）、肌酐（Scr）、血尿酸（SUA）更高。除HDL-C外，胆囊结石组的所有这些因素也更高。脂肪肝患者胆囊结石和息肉的患病率高于无脂肪肝的参与者。
辽宁省胆囊结石和息肉的患病率因性别、居住城市的经济状况、BMI和代谢指标而异。
