Department of Orthopaedics, International Science and Technology Cooperation Base of Spinal Cord Injury, Tianjin Key Laboratory of Spine and Spinal Cord, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin, 300052, People's Republic of China.
Department of Orthopaedics, Qilu Hospital, Shandong University Centre for Orthopaedics, Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, 107 Wenhuaxi Road, Jinan, Shandong, 250012, People's Republic of China.
Arch Osteoporos. 2022 May 12;17(1):78. doi: 10.1007/s11657-022-01113-w.
This study provides a national estimate of the incidence of hospitalizations and assesses the clinical features and outcomes during inpatient admission due to osteoporotic fractures diagnosed by ICD-10-CM/PCS among the elderly in the USA, using the US Nationwide Inpatient Sample, 2016-2018.
To provide a national estimate of the incidence of hospitalizations and assess the clinical features and outcomes during inpatient admission due to osteoporotic fractures (OFs) among the elderly in the USA.
The study included all inpatients aged 65 years and older who participated in the US Nationwide Inpatient Sample (NIS). We conducted a retrospective analysis of hospitalizations with OFs diagnosed by the International Classification of Diseases, Tenth Revision, Clinical Modification/Procedure Coding System (ICD-10-CM/PCS), using the US NIS, 2016-2018. Trends in epidemiological characteristics and outcomes were calculated by annual percentage change (APC).
From 2016 to 2018, there were an estimated 0.16 million hospitalizations for OFs, and the estimated annual incidence rate changed from 995 cases per 1 million persons in 2016 to 1114 cases per 1 million persons in 2018 (APC, 5.8% [95% CI, 0.0 to 12.0]; P > 0.05). Over two-thirds of the patients (68.2%) were age-related osteoporosis with current pathological fracture, and OFs were more likely to occur in vertebra (51.7%) and femur (34.7%). During the hospitalization, the average length of stay (LOS) was 5.83 days, the average cost reached $60,901.04, and the overall mortality was 2.3%. All outcomes including LOS, average cost and mortality did not change significantly in 2016-2018 (all P values for trend were over 0.05).
Between 2016 and 2018, the incidence rate of OFs remained relatively stable, but the total number of cases was huge. OFs was predominantly age-related, mostly in vertebrae and femurs, with relatively stable cost and mortality during hospitalization.
提供美国老年人骨质疏松性骨折（OFs）住院发病率的全国估计，并评估 2016-2018 年美国全国住院患者样本（NIS）中因 ICD-10-CM/PCS 诊断的 OF 住院期间的临床特征和结局。
本研究纳入了所有参与美国全国住院患者样本（NIS）的年龄在 65 岁及以上的住院患者。我们对 2016-2018 年因 ICD-10-CM/PCS 诊断为 OF 的住院患者进行了回顾性分析。通过每年百分比变化（APC）计算流行病学特征和结局的趋势。
2016 年至 2018 年，估计有 16 万例 OF 住院，估计年发病率从 2016 年的每 100 万人 995 例上升至 2018 年的每 100 万人 1114 例（APC，5.8%[95%CI，0.0 至 12.0]；P>0.05）。超过三分之二的患者（68.2%）为年龄相关性骨质疏松症伴当前病理性骨折，OF 更易发生于椎体（51.7%）和股骨（34.7%）。住院期间，平均住院时间（LOS）为 5.83 天，平均费用达到 60901.04 美元，总死亡率为 2.3%。2016-2018 年期间，所有结局（包括 LOS、平均费用和死亡率）均无显著变化（所有趋势 P 值均>0.05）。
2016 年至 2018 年，OF 的发病率保持相对稳定，但病例总数巨大。OF 主要与年龄有关，主要发生在椎体和股骨，住院期间的费用和死亡率相对稳定。
