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人工主动脉瓣膜的诺卡菌性心内膜炎。

Nocardial endocarditis of an aortic valve prosthesis.

作者信息

Ertl G, Schaal K P, Kochsiek K

出版信息

Br Heart J. 1987 Apr;57(4):384-6. doi: 10.1136/hrt.57.4.384.

DOI:10.1136/hrt.57.4.384
PMID:3555567
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1277181/
Abstract

The organism responsible for endocarditis of a prosthetic aortic valve was identified as Nocardia asteroides. The patient was treated with intravenous amikacin (250 mg four times a day) and intravenous imipenem (1.5 g four times a day). The valve was replaced under this new antibiotic regimen. This is the first report of survival after prosthetic valve nocardiosis.

摘要

人工主动脉瓣膜心内膜炎的病原体被鉴定为星形诺卡菌。患者接受静脉注射阿米卡星（每日4次，每次250毫克）和静脉注射亚胺培南（每日4次，每次1.5克）治疗。在这种新的抗生素治疗方案下进行了瓣膜置换。这是人工瓣膜诺卡菌病后存活的首例报告。

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1
Nocardial endocarditis of an aortic valve prosthesis.人工主动脉瓣膜的诺卡菌性心内膜炎。
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本文引用的文献

1
In vitro susceptibility of Nocardia asteroides to N-formimidoyl thienamycin and several cephalosporins.星形诺卡菌对N-甲酰亚胺硫霉素及几种头孢菌素的体外敏感性
Antimicrob Agents Chemother. 1981 Dec;20(6):841-2. doi: 10.1128/AAC.20.6.841.
2
Prosthetic valve endocarditis.人工瓣膜心内膜炎
Circulation. 1984 Feb;69(2):223-32. doi: 10.1161/01.cir.69.2.223.
3
Susceptibility of Nocardia asteroides to 46 antibiotics, including 22 beta-lactams.星形诺卡菌对46种抗生素（包括22种β-内酰胺类抗生素）的敏感性。
Antimicrob Agents Chemother. 1983 Feb;23(2):248-51. doi: 10.1128/AAC.23.2.248.
4
Nocardial endocarditis following mitral valve replacement.二尖瓣置换术后诺卡菌性心内膜炎
Chest. 1973 Feb;63(2):276-8. doi: 10.1378/chest.63.2.276.
5
Diagnostic and therapeutic considerations in Nocardia asteroides infection.星形诺卡菌感染的诊断与治疗考量
Medicine (Baltimore). 1974 Sep;53(5):391-401. doi: 10.1097/00005792-197409000-00005.
6
[New effective therapy of systemic infection with Nocardia asteroides].
Dtsch Med Wochenschr. 1985 Nov 8;110(45):1733-7. doi: 10.1055/s-2008-1069079.
7
Prosthetic valve endocarditis resulting from Nocardia asteroides.由星状诺卡菌引起的人工瓣膜心内膜炎。
Br Heart J. 1979 Jan;41(1):125-7. doi: 10.1136/hrt.41.1.125.