星形诺卡菌对46种抗生素（包括22种β-内酰胺类抗生素）的敏感性。
Susceptibility of Nocardia asteroides to 46 antibiotics, including 22 beta-lactams.
作者信息
Gutmann L, Goldstein F W, Kitzis M D, Hautefort B, Darmon C, Acar J F
出版信息
Antimicrob Agents Chemother. 1983 Feb;23(2):248-51. doi: 10.1128/AAC.23.2.248.
Abstract
Twelve Nocardia asteroides isolates were tested for their susceptibility to 46 antibiotics by the agar dilution method. N-Formimidoyl thienamycin was the most active of 22 beta-lactam antibiotics, inhibiting 11 of the 12 strains at 1 microgram/ml. Penicillins, including ureidopenicillins, showed poor activity. Cefotaxime, ceftriaxone, and especially cefuroxime had the best activities of the cephalosporins tested. Among the other antibiotics, amikacin and minocycline, respectively, inhibited all of the strains tested at 0.5 and 4 micrograms/ml.
摘要
采用琼脂稀释法对12株星形诺卡菌分离株进行了46种抗生素的敏感性测试。N-甲酰亚胺硫霉素是22种β-内酰胺类抗生素中活性最强的，在1微克/毫升时可抑制12株菌株中的11株。包括脲基青霉素在内的青霉素类活性较差。头孢噻肟、头孢曲松，尤其是头孢呋辛在测试的头孢菌素中活性最佳。在其他抗生素中，阿米卡星和米诺环素分别在0.5微克/毫升和4微克/毫升时抑制了所有测试菌株。
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本文引用的文献
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