Institute of Plant and Microbial Biology and Zürich-Basel Plant Science Center, University of Zürich, Zürich, Switzerland.
The Sainsbury Laboratory, University of East Anglia, Norwich, UK.
EMBO J. 2022 Jun 14;41(12):e110741. doi: 10.15252/embj.2022110741. Epub 2022 May 13.
Calcium ions function as a key second messenger ion in eukaryotes. Spatially and temporally defined cytoplasmic Ca signals are shaped through the concerted activity of ion channels, exchangers, and pumps in response to diverse stimuli; these signals are then decoded through the activity of Ca -binding sensor proteins. In plants, Ca signaling is central to both pattern- and effector-triggered immunity, with the generation of characteristic cytoplasmic Ca elevations in response to potential pathogens being common to both. However, despite their importance, and a long history of scientific interest, the transport proteins that shape Ca signals and their integration remain poorly characterized. Here, we discuss recent work that has both shed light on and deepened the mysteries of Ca signaling in plant immunity.
钙离子在真核生物中作为关键的第二信使离子发挥作用。细胞质 Ca 信号的时空特异性是通过离子通道、交换器和泵的协同活动来塑造的，以响应各种刺激；然后通过 Ca 结合传感器蛋白的活性来解码这些信号。在植物中，Ca 信号是模式触发免疫和效应物触发免疫的核心，对潜在病原体的反应产生特征性的细胞质 Ca 升高在两者中都是常见的。然而，尽管它们很重要，并且具有很长的科学研究历史，但塑造 Ca 信号及其整合的转运蛋白仍未得到很好的描述。在这里，我们讨论了最近的工作，这些工作既揭示了植物免疫中 Ca 信号的奥秘，也加深了对其的理解。
